Project Grant R01EY036825

Award Date 5/1/25
Completion Date 4/30/29
Dollars Obligated $562K
Federal Grant Program
93.867
Assistance Type
Project Grant
Place of Performance
Birmingham, AL 35294, USA
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The National Eye Institute (NEI) awarded a $228,718 Project Grant (CFDA 93.867 - Vision Research) to the University of California, Los Angeles (UCLA) to characterize the visual properties and transcriptomic signatures of excitatory neurons in the primary visual cortex (V1) of mice. The project aims to establish correlations between cell type and visual function in V1 by combining in-vivo two-photon calcium imaging to study neuronal receptive fields with expansion-assisted iterative FISH to...
This $157,568 Project Grant award from the National Eye Institute (NEI) Vision Research program (CFDA 93.867) supports research to understand the neural mechanisms underlying visual encoding and behavior in the context of retinal degeneration. The award recipient, The Regents of the University of California, San Francisco (UCSF), will leverage a mouse model of selective cone degeneration to investigate the impact of cone loss on noise correlations between direction-selective retinal ganglion...
The National Eye Institute (NEI) has awarded a $741,499 Project Grant (CFDA 93.867 - Vision Research) to the University of California, Davis to study the functional organization of direct and transthalamic pathways used by cortical areas to communicate in the visual system. The primary goal is to understand how the separate direct and transthalamic pathways between the primary (V1) and secondary (V2) visual cortical areas in mice and monkeys facilitate visual processing and communication....
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The National Eye Institute (NEI) awarded a $611,546 federal Project Grant under the Vision Research program (CFDA 93.867) to the University of California, Berkeley. This grant, titled "CRCNS: COMPUTATIONS AND NEURAL MECHANISMS IN SUSTAINED PERCEPTION IN HUMANS", aims to investigate how the brain supports sustained perception of longer visual stimuli, addressing a gap in the current understanding of human perceptual experience. The project has three specific objectives: 1) examining the...
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The National Eye Institute (NEI) awarded a $562,215 federal Project Grant (CFDA 93.867 Vision Research) to the University of Alabama at Birmingham (UAB) to conduct research on the elementary cone photoreceptor representation in the primary visual cortex of the brain. The research aims to use adaptive optics technology to overcome optical aberrations and measure neural responses in the visual cortex at a cone-resolved level in non-human primates. Key objectives include determining the number and types of cone photoreceptors that comprise a visual cortex neuron's receptive field, assessing the response of a single cortical neuron to a single cone, and evaluating how cortical neurons receiving input from different cone compositions project to secondary visual cortex. This research may provide insights into visual processing mechanisms and aid earlier detection of retinal diseases. The project will be conducted from May 2025 through April 2029.

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