Project Grant R01ES039042
- The National Institute of Environmental Health Sciences awarded Central Michigan University $394,165 on June 11, 2026, under the Environmental Health program (CFDA 93.113) to investigate how methylmercury exposure disrupts neural circuits controlling emotion and cognition in the prefrontal and insular cortices. The research applies an integrative approach combining systems neurophysiology, synaptic, and molecular-level analysis to determine in vivo effects of methylmercury on these brain...
- The National Institute of Environmental Health Sciences awarded Michigan State University $402,066 on September 27, 2025, under the Environmental Health program (CFDA 93.113) to investigate how the epicardium and the IRE1 signaling pathway mediate the effects of environmental chemical exposure on cardiac function. The project employs three-dimensional human heart organoids derived from induced pluripotent stem cells to model the impact of per- and polyfluoroalkyl substances (PFAS) on lipid...
- The National Institute of Environmental Health Sciences awarded Worcester Polytechnic Institute $400,753 on July 1, 2026, under the Environmental Health program (CFDA 93.113) to develop engineered probiotic bacteria for lead toxin elimination. The award funds research into cost-effective methods to reduce lead exposure and cumulative lead poisoning, which disproportionately affects low-income communities and causes permanent neurotoxic effects, neurodevelopmental anomalies in children, and...
- The National Institute of Environmental Health Sciences awarded the University of Washington $180,332 on February 21, 2026, under the Environmental Health program (CFDA 93.113) to develop large-scale, multidimensional reference databases of ToxCast compounds and their metabolites using ion mobility-mass spectrometry (IM-MS) for human exposome applications. The project addresses analytical challenges in measuring the chemical exposome—the complete array of non-genetic environmental factors...
- The National Institute of Environmental Health Sciences awarded the University of Wisconsin–Madison $153,282 on October 1, 2025, under the Environmental Health program (CFDA 93.113) to support research on the role of estrogen receptor beta in polychlorinated biphenyls impacts on bladder function. The research investigates how in utero and lactational exposure to human-relevant polychlorinated biphenyl mixtures alters urinary voiding function in mice through estrogen receptor beta activation...
- The National Institute of Environmental Health Sciences awarded Michigan State University $144,254 on February 1, 2026, under the Environmental Health program (CFDA 93.113) to support postdoctoral training and research on metabolism disrupting chemical exposures and maternal metabolic health in pregnancy. The award funds comprehensive training for Maria Cinzori in environmental epidemiology and perinatal health research, with mentorship from an interdisciplinary team experienced in environmental...
- The National Institute of Environmental Health Sciences awarded the University of Rochester $415,613 under the Environmental Health program (CFDA 93.113) on February 24, 2026, to investigate how pregnancy and the maternal gut microbiome influence methylmercury metabolism and elimination in pregnant women and fetuses. The research optimizes previously developed tools to monitor methylmercury metabolism and excretion in non-pregnant adults, applying them to pregnant women who consume fish...
- The National Institute of Environmental Health Sciences awarded the University of Wisconsin - Madison $3,343,688 on September 1, 2026, under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) to examine pathways of per- and polyfluoroalkyl substances (PFAS) exposure and their impacts on hyperlipidemia in a rural community impacted by land spreading of biosolids and sludge. The research addresses three gaps in PFAS science. The study will examine how lipid...
- The National Institute of Environmental Health Sciences awarded Boston University Medical Campus $197,600 on November 1, 2025, under the Environmental Health program (CFDA 93.113) to examine early-life exposure to ferroalloy metal mixtures and adolescent cognition. The research investigates how exposure to neuroactive metals—manganese, lead, chromium, and copper—released through ferroalloy industrial emissions affects neurodevelopment in children and adolescents living near such facilities....
- The National Institute of Environmental Health Sciences awarded The Washington University $3.141830 million on September 26, 2025, under the Environmental Health program (CFDA 93.113) to investigate prenatal chemical exposures, childhood adversity, resilience, and depression risk. The research examines individual and joint effects of prenatal exposure to polybrominated diphenyl ethers (PBDEs) and organophosphate esters (OPEs)—legacy and replacement flame retardant chemicals—on maternal...
The National Institute of Environmental Health Sciences awarded The Medical College of Wisconsin, Inc., $706,420 on August 1, 2026, under the Environmental Health program (CFDA 93.113) to develop and test Gegoo Myaajyang Gkendmang (Knowing What We Eat), a mobile application designed to reduce dietary exposure to chemical contaminants in Great Lakes Anishinaabe communities. The award funds characterization of dietary patterns and quantification of contaminants in local and subsistence foods including wild rice, venison, fish, berries, and garden produce among the Inter-Tribal Council of Michigan and its 11 member tribes. The application will expand upon existing National Institute of Environmental Health Sciences-funded software that previously provided fish consumption advice, now incorporating recipes, seasonal guides, and personalized recommendations to promote diets that reduce exposure to obesogenic contaminants such as PFAS, BPA, DEHP, and TCDD. The project will conduct a stepped-wedge cluster randomized trial with 300 participants across the 11 tribes over 12 months, targeting 17.5 percent improvement in environmental health literacy and increased likelihood of achieving dietary scenarios with 30 to 50 percent lower contamination than conventional U.S. diets. Performance occurs at The Medical College of Wisconsin's location in Wauwatosa, Wisconsin. The award period runs from August 1, 2026, through July 31, 2031. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $706.4k | 7/29/26 |