This $637,553 Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program will fund research to assess the toxicity, uptake, and biodistribution of environmentally relevant micro-nanoplastics (MNPs) and the role of intestinal inflammation. The 5-year project led by Rutgers, The State University of New Jersey will: Develop and characterize MNPs composed of major plastic polymers to enable accurate quantification and...
This Project Grant award of $453,688.00 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program aims to investigate the molecular mechanisms linking microplastics exposure to the progression of colorectal cancer (CRC). The research project, conducted by the University of New Mexico Health Sciences Center, will unveil how microplastics trigger Piezo1-dependent oxidative stress and Hypoxia Inducible Factor (HIF)-3A...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $428,387 to Purdue University to investigate the toxicological impacts of environmentally relevant nanoplastics. The research aims to quantify how nanoplastics interact with common environmental contaminants and biomolecules, and how these interactions influence cellular responses and toxicity. Purdue will develop a novel procedure to...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $429,504 to New York University (NYU) School of Medicine to characterize human exposure to microplastics during pregnancy. The overarching aim is to leverage existing infrastructure from the NYU Children's Environmental Health Study (NYU CHES) to measure and characterize microplastics in placental tissue collected from the general...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program provides $404,989 to investigate the mechanisms of nanoplastic transport in the brain. The key research objectives are to: 1) examine the uptake and distribution of nanoplastics in the mouse olfactory system, and 2) study how nanoplastics may interact with kinesin motor proteins to be actively transported into the brain. This two-year...
This federal Project Grant award of $352,126, funded by the National Science Foundation (NSF) Engineering program (CFDA 47.041), will support research at the University of Hawaii at Manoa to establish a pioneering microplastic library in Hawaii and study the biophysical mechanisms of how micro/nanoplastics impact respiratory health. The key objectives of this 3-year award are to: 1) Create a unique collection of microplastic samples sourced from the shorelines of Oahu Island, providing...
This $191,801 National Science Foundation Project Grant under the Integrative Activities program will support research into the properties and toxicity of microplastics and nanoplastics through a combination of experimental and computational methods. Professor B. Rasulev of North Dakota State University will lead an interdisciplinary collaboration with Rutgers University to characterize micro- and nanoplastic materials experimentally and computationally. Structure-toxicity analysis and...
This federal Project Grant award of $120,000.00 from the U.S. Department of Defense Research, Development and Engineering Command (RDECOM), under the Basic Scientific Research program (CFDA 12.431), aims to advance fundamental knowledge in environmental degradation of micro- and nano-plastics. The primary objective is to investigate the changes in surface and bulk material properties of weathered plastics due to urban riverine biofilm formation. The award was granted to the University of...
This $400,000 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) will support research at the University of Southern California (USC) to study the impacts of environmental nanoplastics on cell membranes. The key objectives are to: 1) develop tools to create and isolate nanoplastic particles that mimic real-world environmental nanoplastics, 2) discover how these nanoplastics can alter cell membrane properties, and 3) understand how specific...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $390,724 to the University of New Mexico to develop a proof-of-concept prototype for a "Standing Wave Acoustics for Nanoplastics Separations" (SWANS) platform. The SWANS system will use acoustic standing waves to rapidly isolate and enrich plastic nanoparticles from various samples, including bottled water, environmental water,...