Project Grant R01ES036522
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $157,500 Project Grant to the Regents of the University of California at Riverside on July 9, 2025, under the Environmental Health program (CFDA 93.113). This two-year award (completion date: July 8, 2027) funds pilot research investigating gene-environment interactions in autism spectrum disorder (ASD) risk through developmental exposure to per- and polyfluoroalkyl substances (PFAS), commonly...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the Regents of the University of Michigan a $3.13 million Project Grant under the Environmental Health program (CFDA 93.113) on September 10, 2025, with completion anticipated by September 9, 2029. The research initiative, conducted at the University of Michigan's Ann Arbor campus, aims to integrate exposome and epigenome analyses to identify determinants of amyotrophic lateral sclerosis...
- Federal Grant Award Summary Drexel University received a $111,199 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective April 3, 2026 through March 31, 2028. The award supports research investigating the role of phthalates and phenols—endocrine-disrupting chemicals (EDCs) found in consumer products—on phenotypic variability in autism and co-occurring neurodevelopmental disorders, obesity, and...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded Icahn School of Medicine at Mount Sinai a $498,000 Project Grant under the Environmental Health program (CFDA 93.113) with an award date of August 25, 2025, and a completion date of July 31, 2028. This R00 career development award supports the investigator's transition to an independent researcher in environmental developmental neuroscience. The primary deliverable is a longitudinal...
- Federal Project Grant Summary Michigan State University received a $100,000 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective September 27, 2025, with a completion date of August 31, 2027. The award funds research investigating the role of the epicardium and inositol-requiring enzyme 1A (IRE1A) in mediating the effects of environmental chemical exposures on cardiac function. The research...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health program (CFDA 93.113), awarded a $246,562 Project Grant to the Icahn School of Medicine at Mount Sinai effective May 1, 2025, with a completion date of December 31, 2027. This research initiative investigates the impact of perinatal metal mixture exposure and prenatal maternal stress on neural and cognitive constructs underlying adolescent risk-taking behaviors. The...
- Federal Grant Award Summary Kaiser Foundation Hospitals, through its Kaiser Foundation Research Institute, received a $699,956 Project Grant from the National Institute of Environmental Health Sciences (CFDA 93.113 - Environmental Health program) awarded September 16, 2025, with completion targeted for June 30, 2030. The research project investigates the association between prenatal exposure to organophosphate ester flame retardants and plasticizers (OPEs)—endocrine-disrupting chemicals of...
- Federal Grant Award Summary Dr. O'Sharkey is conducting research funded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) through a K99/R00 career development award totaling $241,326, with performance occurring at the University of California, Los Angeles. The project, "Uncovering the Impact of Air Pollution Sources on Autism Spectrum Disorder: A Metabolomic Approach to Identifying Critical Biological Pathways," aims...
- Federal Grant Award Summary Michigan State University's Henry Ford Health+Michigan State University Health Sciences partnership received a $2.86 million Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded on August 15, 2025, with a completion date of July 31, 2029. This research project aims to model the effects of cadmium exposure on Alzheimer's disease (AD) pathology and neurodegeneration through a multi-principal investigator approach...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $124,728 Project Grant to the University of Pennsylvania on September 8, 2025, under the Environmental Health program (CFDA 93.113) to conduct research on gestational and childhood exposure to endocrine-disrupting chemicals (EDCs) and their effects on adolescent neurobehavior. The award, scheduled for completion by August 31, 2027, funds a phased research initiative investigating how...
The National Institute of Environmental Health Sciences (NIEHS) awarded Henry Ford Health + Michigan State University Health Sciences a $790,980 Project Grant under the Environmental Health program (CFDA 93.113) effective April 1, 2026, with completion targeted for January 31, 2031. The research project investigates the epigenetic control mechanisms of high-confidence autism spectrum disorder (ASD) genes, specifically examining how environmental exposures and genetic factors converge to influence ASD risk. The research addresses four established ASD risk factors: male sex, loss-of-function mutations in chromodomain helicase DNA binding protein 8 (CHD8), environmental exposures to valproic acid and fine particulate matter air pollution, and identified genetic loci on chromosomes 5P14.1 and 20P12.1 involving long noncoding RNAs. The project deliverables include mechanistic studies and translational research examining how environmental factors reduce CHD8 expression in human neural progenitor cells and cerebral organoids, identification of functional elements and epigenetic pathways underlying ASD susceptibility, and development of evidence-based approaches to understand gene-environment interactions in neurodevelopmental disorders. Research conducted at the Michigan-based institution will contribute to the NIEHS mission of translating environmental health knowledge into strategies that reduce disease burden and promote health outcomes, particularly for a highly prevalent neurodevelopmental disorder that disproportionately affects males and currently lacks targeted therapeutic interventions for core symptoms.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $791.0k | 4/1/26 |