Project Grant R01ES036237
- This Project Grant award of $284,614 from the U.S. Department of Housing and Urban Development's Office of Policy Development and Research (CFDA 14.506 - General Research and Technology Activity) will support activities to prepare for a third wave of data collection for the Housing and Children's Healthy Development (HCHD) study. Key tasks include locating and engaging study participants, developing and revising questionnaires, and conducting sub-group analyses on hypertension response to a...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $419,011 to Emory University to develop innovative dimensionality reduction techniques for assessing the joint health effects of air pollution mixtures. The research aims to advance causal modeling approaches that preserve the relationships between air pollutants and health outcomes, in order to provide more accurate assessments of the public...
- This Cooperative Agreement award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) Federal Grant Program, will provide $394,309 to the University of Arkansas for Medical Sciences (UAMS) to maintain, enrich, and enable broader use of data and sample resources for the Arkansas Rural Community Health Study (ARCH) cohort. The key products and services to be delivered include: Expanding collaboration and hiring of underrepresented...
- This $440,770 Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), will support a rapid, longitudinal study on the community health and air quality implications of the retirement of two petroleum refineries in the South Bay region of Los Angeles. The objective is to determine whether the closure of these refineries, which are major stationary sources of hazardous air pollutants, results in...
- The National Institute of Environmental Health Sciences (NIEHS), through the Environmental Health federal grant program (CFDA 93.113), awarded a $481,500 Project Grant to the Children's Hospital Medical Center in Cincinnati, OH. The grant titled "Enhancing the Sustainability and Impact of Geomarker Assessment Tools for Research" aims to enhance the scalability, interoperability, and reusability of the DEGAUSS open-source research tool. The project will leverage advances in computing to...
- This Project Grant award of $430,252 from the National Science Foundation (NSF) Social, Behavioral, and Economic Sciences (CFDA 47.075) program supports a collaborative multi-year research project examining the multi-sectoral determinants of health in low-income communities globally. The research uses qualitative and quantitative methods to investigate the formulation, interpretation, translation, and implementation of health policies across local, national, and transnational scales. The project...
- This Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) provides $716,587 to Boston Children's Hospital to advance equity in rare disease genomic research. The key objectives are to: Develop and implement a Diversity, Equity, and Inclusion toolkit within the Broad Institute's Rare Genomes Project to improve engagement and participation from historically underrepresented populations in rare disease genomic studies. This will involve...
- This R21 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $433,950 to the University of California, Davis to study the impact of wildfire smoke exposure on lung injury and disease in pediatric populations. The key objectives are to: 1) Define the contribution of age on the toxicity of wood smoke particles in respiratory and alveolar epithelium, 2) Investigate the effect of early life wood...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), provides $147,486 to Trustees of Boston University's Boston University Medical Campus to conduct research on the associations between metal exposure, the urinary microbiome, and kidney health among adolescents in Central America. The research activities include quantifying toenail metal concentrations using a portable X-ray fluorescent...
- This Project Grant award of $734,151, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support a comprehensive research study on the impact of HIV exposure and toxic metal exposure on neurodevelopmental outcomes among children in East and Southern Africa. The key objectives of the project are to: 1) test for lead exposure levels and determine the association between...
COLLABORATIVE DEVELOPMENT OF ETHICAL REPORT-BACK GUIDELINES FOR HOUSEHOLDEXPOSURE RESEARCH - PROJECT SUMMARY HOME-BASED EXPOSURES AND POOR HOUSING QUALITY CONTRIBUTE TO HEALTH INEQUITIES (E.G., ASTHMA, LEAD, REPRODUCTIVE HEALTH ETC.) AND ARE A DRIVING FORCE BEHIND MANY ENVIRONMENTAL INJUSTICES. HOUSEHOLD EXPOSURE RESEARCH CAN INFORM SOLUTIONS TO THESE URGENT PROBLEMS. RESPONSIBLE REPORT-BACK OF INDIVIDUAL-LEVEL RESEARCH RESULTS (RBRR) FROM HOUSEHOLD EXPOSURE STUDIES IS ESSENTIAL TO PROMOTE CHANGES IN BEHAVIOR, HOUSING PROVIDER PRACTICES, COMMUNITY ACTION, AND POLICIES TO IMPROVE HEALTH. WHILE HIGH LEVEL REPORT-BACK PRINCIPLES HAVE BEEN DEVELOPED FOR ENVIRONMENTAL HEALTH RESEARCH, THESE DO NOT PROVIDE SPECIFIC GUIDANCE ON THE UNIQUE ETHICAL CHALLENGES OF HOUSEHOLD EXPOSURE RESEARCH. RBRR FOR HOUSEHOLD EXPOSURE STUDIES RAISES A NUMBER OF ETHICALLY CONTENTIOUS ISSUES RELATED TO THE ACTIONABILITY OF RESULTS, PARTICIPANTS' HOUSING STATUS (E.G., INCOME LEVEL, OWNER/RENTER, PUBLIC/PRIVATE HOUSING), AND THE INTERESTS OF THIRD PARTIES (INCLUDING FAMILY MEMBERS, NEIGHBORS, HEALTH PROFESSIONALS, LANDLORDS AND COMMUNITY LEADERS), AMONG OTHERS. THIS PROJECT AIMS TO PROMOTE HEALTH EQUITY AND IMPROVE COMMUNICATION BY DEVELOPING GUIDELINES FOR RBRR FOR HOUSEHOLD EXPOSURE STUDIES IN WAYS THAT RESPECT PARTICIPANT PREFERENCES AND INFORM APPROPRIATE ACTION. WE BUILD ON A LONGSTANDING COMMUNITY PARTNERSHIP WITH ROCHESTER ENERGY EFFICIENCY AND WEATHERIZATION (RENEW) AND ACTIVELY INVOLVE A STAKEHOLDER ADVISORY BOARD THAT REPRESENTS THE DIVERSE PERSPECTIVES OF COMMUNITY GROUPS, HOUSING PROVIDERS, IRBS, PUBLIC HEALTH PROFESSIONALS AND OTHERS WHO MAY BE AFFECTED BY RBRR. WE INTEGRATE PRIOR REPORT BACK STUDIES BY RECRUITING PARTICIPANTS FROM SEVERAL PAST HOUSING EXPOSURE RESEARCH STUDIES, INCLUDING ROC HOME, TO PROVIDE FORMATIVE INPUT TO AIM 2. SUCCESSFUL COMPLETION OF THIS PROJECT WILL RESULT IN: (AIM 1) A PHILOSOPHICALLY AND EMPIRICALLY-INFORMED TYPOLOGY OF THE KEY ETHICAL QUESTIONS FACED BY RESEARCHERS DURING RBRR OF HOUSEHOLD EXPOSURE STUDIES; (AIM 2) A TOOL FOR ELICITING PARTICIPANTS' PREFERENCES FOR RBRR IN HOUSEHOLD EXPOSURE RESEARCH; AND (AIM 3) DECISION-SUPPORT GUIDELINES TO HELP RESEARCH TEAMS RETURN INDIVIDUAL RESULTS RESPONSIBLY. OUR COLLABORATIVE APPROACH WILL USE A RIGOROUS TRANSDISCIPLINARY FRAMEWORK TO FILL A CRUCIAL GAP IN REPORT-BACK GUIDANCE FOR HOUSEHOLD EXPOSURE RESEARCH AND WILL SERVE AS A MODEL FOR FUTURE RESEARCH ON REPORT-BACK OF ENVIRONMENTAL AND NON-GENOMIC RESEARCH RESULTS.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $179.8k | 8/5/25 | ||
| Not listed | $0 | 7/31/25 | ||
| Not listed | $0 | 6/11/25 | ||
| Not listed | $0 | 6/11/25 | ||
| Not listed | $0 | 8/28/24 |