This Project Grant award, funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), will support research to investigate the association between arsenic exposure and cancer incidence among residents with private wells in New Mexico's border counties. The research team from New Mexico State University will use urine biomarkers to detect arsenic contamination and identify DNA damage, oxidative stress, and...
This Project Grant award of $453,688.00 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program aims to investigate the molecular mechanisms linking microplastics exposure to the progression of colorectal cancer (CRC). The research project, conducted by the University of New Mexico Health Sciences Center, will unveil how microplastics trigger Piezo1-dependent oxidative stress and Hypoxia Inducible Factor (HIF)-3A...
This federal Project Grant award, with ID R35GM154651, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The $381,250 award, effective September 1, 2024 through August 31, 2029, will support research at the University of New Mexico Health Sciences Center (UNM HSC) to investigate the cellular mechanisms underlying the response to lysosomal damage. The research aims to establish the function of...
This Project Grant award of $749,901.00, provided by the National Institute of Environmental Health Sciences (CFDA 93.113 Environmental Health), supports research to elucidate the origins of mutational landscapes in cancer. The key objectives are to: Generate DNA samples and use mass spectrometry to characterize the DNA adductome (types and amounts of DNA lesions) from exposure to environmental mutagens like 1,2,3-trichloropropane, bromochloroacetic acid, and furan. Map the genomic positions...
The University of New Mexico was awarded a $497,969 Project Grant from the National Science Foundation Division of Emerging Frontiers under the Biological Sciences federal grant program (CFDA 47.074) for the period of September 1, 2021 through August 31, 2026. The grant funds collaborative research titled "COLLABORATIVE RESEARCH: MIM: THE IMPACT OF THE FUNGAL MICROBIOME IN METAL TOLERANCE AND SOIL BIOGEOCHEMICAL TRANSFORMATIONS." The research aims to advance understanding of major...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) supports the development of a field-deployable analyzer for detecting and quantifying trace levels of uranyl (uranium) in water. The $173,075 award to Ondavia, Inc., a for-profit manufacturer of advanced chemical analysis technologies, aims to create a Surface-Enhanced Raman Spectroscopy (SERS)-based...
This Project Grant award, valued at $1,542,717.00 and funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to decipher protein ubiquitination and its role in cellular processes. The University of Delaware, the primary awardee, will use chemical biology tools to investigate the recognition and cleavage of atypical polyubiquitin chains and ubiquitinated proteins by deubiquitinases (DUBs)....
The National Institute of General Medical Sciences (NIGMS), through its Biomedical Research and Research Training program (CFDA 93.859), awarded a $355,584 Project Grant to the New Mexico Institute of Mining and Technology (New Mexico Tech) on August 18, 2023. This funding will support research to determine the biochemical basis and functional implications of the interaction between the proteins XRN2 and DDX23, and explore their cooperative role in regulating RNA-DNA hybrid structures...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $1,113,999.00 to the University of Denver to elucidate the structure and functions of microbially-derived metallophores and their role in modulating microbe-microbe and community interactions within human microbiomes. The key objectives of this 5-year research project are to: 1) identify metallophores produced by the...
This Project Grant award of $466,125.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training (CFDA 93.859) program, supports research to identify and characterize key metabolic control mechanisms. The research aims to: Study the physiological importance of an evolutionarily conserved mechanism by which cells sense pyrimidine levels, using genetically engineered cell and mouse models. This will delineate the role of allosteric...