Project Grant R01EB038309
- This National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) Federal Grant Program (CFDA 47.070) award of $1,200,000 provides funding to the University of California, Berkeley from October 1, 2024 to September 30, 2028 to develop innovative sensing technologies that integrate DNA nanotechnology and CMOS electronics for next-generation diagnostics. The key objectives of this project grant are to: (1) develop molecular engineering techniques using DNA origami...
- This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will develop living biosensors to detect and analyze DNA at the single-base level without requiring sample purification or specialized equipment. The $565,614 award will produce a hybrid living biosensor/lateral flow assay that can rapidly detect target DNA sequences,...
- This $360,320 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) aims to develop and test the first continuous electrochemical sensors for monitoring large protein and peptide analytes, such as insulin and cardiac markers. The project, titled "Aptamer Tagging with Redox Quenchers: A Critical Breakthrough in the Sensitivity of...
- This $399,935 National Science Foundation (NSF) Project Grant Award under the Computer and Information Science and Engineering program (CFDA 47.070) aims to develop a portable and cost-effective biomedical diagnostic system in the form of an integrated lab-on-a-chip platform produced using additive manufacturing techniques. The key products and services to be delivered include: Advancing 3D manufacturing techniques, particularly in electrode printing, to enhance fabrication precision and...
- This federal Project Grant award for $412,276 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), supports the development of an optofluidic biosensor using an integrated waveguide spectrometer. The key objectives are to: 1) demonstrate detection of individual nanoparticles on an integrated multi-mode interference (MMI) waveguide spectrometer optimized...
- This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I Project Grant, awarded under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, provides $304,966 to support the development of a portable, rapid point-of-care diagnostic device capable of simultaneously detecting and quantifying multiple blood-based biomarkers. The project aims to create an integrated cartridge/analyzer system that can automate serum separation and buffer dilution to...
- This National Science Foundation (NSF) Project Grant award for $380,074, awarded on September 1, 2024, aims to develop a platform for instrument-free, easy-to-interpret quantitative analysis of molecular biomarkers. The project will produce a general methodology adaptable to a range of molecular targets, including potential new agents. The key products to be delivered include: A "yes/no" output for quantitative measurement, enabled through stoichiometry and negative cooperativity-based...
- The University of California, Irvine was awarded a $392,500 Project Grant from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) to develop the Maternal Obstetric Monitoring System (MOMS), a wearable device for early detection of postpartum hemorrhage (PPH). The project aims to design and validate an alpha prototype sensor that integrates a MEMS-based blood pressure sensor and a continuous signal integration (CSI) sensor, as well as determine design...
- The federal Project Grant award, funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a real-time, continuous monitoring platform to track cardiac troponin I (cTnI) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels alongside electrocardiogram (ECG) readings. The $127,926 award to The Leland Stanford Junior University...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $413,067 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to Colorado State University to develop a new class of electrochemical biosensors that use engineered binding proteins. The goal is to simplify fabrication and improve performance of electrochemical sensors, which have potential for inexpensive, sensitive, and quantitative...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the federal Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $2,328,157 to develop a miniaturized, disposable CMOS-based point-of-care (POC) system for detecting biomarkers in complex samples. The key innovations include aptamer switches that generate binding-specific electrochemical signals without sample preparation, and a millimeter-sized single-chip CMOS electronics that houses and measures multiple aptamer switches and wirelessly transmits the results to a smartphone. This system is specifically designed to measure two urine metabolites crucial for early detection of preeclampsia, a prominent contributor to maternal mortality in developing nations. The project, with a performance period from September 2025 to August 2029, will be conducted by the University of California, Berkeley.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.3m | 9/12/25 |