Project Grant R01EB038048
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $122,260 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) effective July 1, 2025 through June 30, 2027. The award supports development of radiofluorination methods and fluorine-18 (18F) labeled prosthetic groups designed to enable rapid, iterative...
- Federal Project Grant Award Summary Duke University received a $722,392 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under CFDA 93.286, Discovery and Applied Research for Technological Innovations to Improve Human Health, awarded March 10, 2026, with completion targeted for February 28, 2030. The project involves developing 4D Smart Epidermal Photoacoustic Tomography (4D-SEPAT), a real-time, longitudinal functional brain imaging technology designed...
- Federal Grant Award Summary North Carolina State University received a $200,138 Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) beginning October 1, 2025, with completion targeted for September 30, 2028. This collaborative research initiative will develop a wireless bioelectronic system for monitoring fentanyl in the brains of freely moving animal models to advance understanding of opioid use disorder (OUD), which affects approximately 3.7% of U.S....
- Federal Grant Award Summary Colorado State University received a $413,067 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective September 1, 2025, through August 31, 2027. The project aims to develop an improved class of electrochemical biosensors utilizing engineered binding proteins to simplify electrode fabrication and enhance...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $420,281 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The award, effective April 1, 2026 through March 31, 2028, supports the design, fabrication, and analytical evaluation of an implantable needle-type nitric oxide (NO) sensor. The project will...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $586,406 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective May 1, 2026 through February 28, 2030. The award funds research and development of Immunomodulatory Self-Assembled Peptides (ISAP), a novel supramolecular...
- Federal Project Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $696,824 Project Grant to the University of North Carolina at Chapel Hill on August 11, 2025, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The project, spanning through June 30, 2029, will develop a novel robust and interpretable multi-modal artificial intelligence/machine learning (AI/ML) framework designed...
- Federal Grant Award Summary Florida State University's Sponsored Research Administration division received a $378,715 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 8, 2025, with completion targeted for June 30, 2030. The Lazenby Lab will develop and advance aptamer-based biosensing probes integrated with scanned probe microscopies to enable high-resolution chemical...
- Federal Grant Award Summary The University of North Carolina at Greensboro received a $1.33 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to develop advanced analytical technologies for unsaturated lipidomics research. The award, effective April 1, 2026, through March 31, 2030, focuses on extending a novel ion chemistry technique called OZNOXESI to enable cost-effective,...
- Federal Cooperative Agreement Award Summary North Carolina Central University (NCCU) received a $424,500 Cooperative Agreement award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective September 1, 2025, through August 31, 2028. The award supports the development and expansion of the Biomedical Engineering, Imaging, and Technology Acceleration...
North Carolina State University received a $691,316 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective June 1, 2026, with a completion date of February 28, 2030. The research will develop advanced aptamer selection and maturation methodologies to create high-performance aptamers for in vivo monitoring of small molecules. The project addresses current limitations in aptamer affinity and specificity under physiological conditions through two primary aims: (1) development of Nuclease-Assisted Systematic Evolution of Ligands by Exponential Enrichment (NA-SELEX), a novel aptamer selection approach that eliminates solid-support requirements and enables simultaneous application of thermodynamic and kinetic stringency; and (2) creation of Motif-SELEX, an innovative aptamer maturation technique designed to significantly enhance aptamer performance. These research deliverables will advance biosensor technology capable of supporting real-time in vivo molecular measurements and chemically responsive materials, with direct applications to biomedical sensing and diagnostic development. The project builds upon preliminary evidence indicating that poor aptamer performance stems from limitations in conventional selection techniques rather than inherent nucleic acid constraints, positioning the work to generate transformative biotechnologies with broad applicability across biomedical imaging and bioengineering domains supported by NIBIB's mission to develop technologies that improve human health through enhanced disease understanding, detection, and treatment.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $691.3k | 5/26/26 |