Project Grant R01EB037685
- This Project Grant award of $452,967.00 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), supports the development of a novel, robot-integrated system for intraoperative creation and annotation of digital 3D models of resection specimens and the residual tumor bed. The goal is to improve the management of positive surgical margins in the resection of oropharyngeal squamous cell carcinoma, which can...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $305,000 to Bullseye Biodevices, Inc. aims to develop a novel biosensing device for rapidly mapping volumetric tumor margins during surgical interventions for cancer. The key product under development is an electromechanical probe and sensor system that can generate real-time, 3D maps of tumor location and boundaries by measuring biophysical properties like force, deformation, and...
- This federal Project Grant award of $695,814 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) supports research to develop artificial intelligence (AI) technologies that enable online adaptive radiation therapy for proton therapy. The key products and services to be delivered through this grant include: 1) Developing an asymmetric autoencoder network...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,205,290 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to the Massachusetts Eye And Ear Infirmary. The grant supports the development of a fluorescence lifetime-based intraoperative imaging system to enhance visualization and real-time feedback for sarcoma surgeries. The project aims to create new tools that can accurately detect...
- This federal Project Grant award of $374,095 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a device that uses an infrared laser to enable local delivery of a high dose of chemotherapy to the surgical cavity after tumor resection. The technology employs thermosensitive liposomal nanoparticles encapsulating chemotherapy agents that...
- This federal Project Grant award of $1,554,122, provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a pioneering dynamic simultaneous localization and mapping (SLAM) approach for real-time tracking of liver surface variations during minimally invasive liver surgery. The project will integrate multiple imaging modalities, including...
- This federal Cooperative Agreement award, issued by the Department of the Interior's Interior Business Center under the Advanced Research Projects Agency for Health (ARPA-H) program (CFDA 93.384), supports the development of a novel imaging technology called "VISION" that enables real-time, high-resolution intraoperative detection of microscopic residual cancer cells during surgical procedures. The $5,160,920 award to the Regents of the University of California, San Francisco aims to...
- This $300,000 Project Grant awarded by the National Science Foundation (NSF) under the Integrative Activities (CFDA 47.083) program supports the development of an innovative, intelligent surgical probe for prostate cancer treatment. The project aims to create an edge artificial intelligence (AI) system-on-chip for bioimpedance analysis that can accurately distinguish cancerous from healthy tissue during prostate removal surgery. The novel technology being developed includes an adaptive filter to...
- This Cooperative Agreement, awarded by the Department of the Interior's Interior Business Center under the Advanced Research Projects Agency for Health (ARPA-H) program (CFDA 93.384), provides $8,945,662.00 in funding to Emory University to develop a functional prototype system called "MARGINCALL" that can rapidly image surgical specimen contours, mark resection margins, and use AI to map cancer and assess tumor proximity to margins. The goal is to reduce current rates of lumpectomy...
- This federal Project Grant award, valued at $306,872 and provided by the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395), aims to develop a new imaging system termed the Multi-Camera Array Scanner (MCAS). The MCAS will enable rapid 3D digitization and automated analysis of thick fine-needle aspiration (FNA) cytology smears, which are a critical first step in the cancer diagnosis pipeline. The project is a collaboration between Ramona Optics Inc., a small...
This Project Grant award of $2,223,201.00, funded by the National Institute of Biomedical Imaging and Bioengineering (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health), supports the development of an Augmented Reality (AR) guidance system with deformation modeling to aid in the relocation of tumor margins during head and neck cancer surgery. The project, conducted by Vanderbilt University, aims to improve the success rate of re-resection procedures by enabling surgeons to more accurately identify and remove residual cancer tissue. The AR system will leverage 3D scanning of the resected specimen and the surgical site to create a deformed virtual model that is projected onto the patient, guiding the surgeon during additional tissue removal. This innovative technology has the potential to significantly reduce positive margin rates and improve patient outcomes in head and neck cancer surgeries.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.2m | 8/4/25 |