Project Grant R01EB036085

Award Date 8/1/24
Completion Date 4/30/28
Dollars Obligated $1.5M
Federal Grant Program
93.286
Assistance Type
Project Grant
Place of Performance
Boston, MA 02215, USA
Similar Awards
This National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) Federal Grant Program (CFDA 47.070) award of $1,200,000 provides funding to the University of California, Berkeley from October 1, 2024 to September 30, 2028 to develop innovative sensing technologies that integrate DNA nanotechnology and CMOS electronics for next-generation diagnostics. The key objectives of this project grant are to: (1) develop molecular engineering techniques using DNA origami...
This $447,747 Project Grant award from the National Science Foundation (NSF) Engineering Program (CFDA 47.041) to Trustees of Boston University will develop a novel plasmonic nanosensor system to detect two important classes of RNA molecules - microRNA (miRNA) biomarkers and SARS-CoV-2 viral RNA. The sensor platform uses DNA structures with nanoparticle probes that undergo conformational changes when binding to target RNAs, altering the plasmonic coupling signal which is detected via two-color...
This Project Grant award of $576,716.86 from the National Institute of Biomedical Imaging and Bioengineering (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) supports research and development of machine learning-enabled microfluidic technologies for characterizing and classifying extracellular vesicles (EVs) from ovarian cancer samples. The award to Northwestern University aims to develop novel EV separation and surface-enhanced Raman...
This $249,000 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), supports the development of a novel split enzyme diagnostic platform for rapid, sensitive detection of protein and small molecule biomarkers at the point of care. The key products and services to be delivered through this grant include: Incorporating binding domains...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), has awarded a $980,779 Project Grant to the University of Cincinnati to develop a deployable and adaptable plasmonic sensing platform for infectious disease surveillance. The project aims to create a highly sensitive and accurate point-of-need diagnostic test capable of detecting multiple genetic biomarkers,...
This $399,935 National Science Foundation (NSF) Project Grant Award under the Computer and Information Science and Engineering program (CFDA 47.070) aims to develop a portable and cost-effective biomedical diagnostic system in the form of an integrated lab-on-a-chip platform produced using additive manufacturing techniques. The key products and services to be delivered include: Advancing 3D manufacturing techniques, particularly in electrode printing, to enhance fabrication precision and...
This $1,399,500 Project Grant award from the National Institutes of Health's Trans-NIH Research Support program (CFDA 93.310) will fund research at the University of Wisconsin - Madison to develop "cellular radio" circuits that can be used to visualize, probe, and perturb the dynamic protein activity in individual cells. The project aims to create genetically-engineered circuits that generate a frequency-modulated, barcoded fluorescent signal to track how the internal state of cells...
The federal Project Grant award R01EB037031, provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will develop living biosensors capable of detecting and analyzing DNA from raw samples without requiring sample purification or specialized equipment. The $257,807 award, spanning from April 2025 to March 2029, will focus on demonstrating the...
This federal Project Grant award from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396) supports the development of a new bio-orthogonal mid-infrared photothermal imaging approach to quantitatively measure various molecular events in cancer cells at the subcellular level. The $407,113 award to Trustees of Boston University will be used to: 1) build a library of nitrile-based probes to sense important molecular events inside cancer cells; 2) develop...
This federal Project Grant award, provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), is supporting research to develop a novel approach to improve the recovery of circulating tumor DNA (ctDNA) from blood samples. The $581,703 award will enable the awardee, The General Hospital Corporation (doing business as Massachusetts General Hospital), to...

This $1,466,982 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) will fund research to develop digital enhancer circuits and self-assembled split recombinases for combinatorial logic sensing. The goal is to create more sensitive and specific cellular diagnostic devices for applications such as ovarian cancer detection. The 4-year project, running from Aug 2024 to Apr 2028, will be conducted by Trustees of Boston University, a private non-profit research institution. The research aims to advance the engineering of recombinase-based genetic circuits to amplify signals and improve the specificity of cell-based diagnostic devices, with potential applications in detecting other pathological conditions like inflammation.

Generated 7/8/25, 1:21 PM