This National Institute of Biomedical Imaging and Bioengineering (NIBIB) federal grant award under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program is for $472,928. The primary aim is to develop the hardware and software necessary to enable concurrent, high-quality acquisition of magnetic resonance imaging (MRI) and deuterium metabolic imaging (DMI) scans on a clinical 3T MRI system. DMI is a novel, non-invasive technique to map in vivo glucose metabolism, which has shown strong potential to supplement anatomical MRI with unique metabolic information, particularly for brain tumor applications. The project will focus on creating a dual-tuned 1H/2H radiofrequency coil and parallel acquisition methods to integrate DMI into a standard clinical brain MRI protocol without increasing total scan time. This will facilitate broader adoption of DMI as an imaging capability at clinical sites to enable further research and validation across diverse patient populations.
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