Project Grant R01DK145897
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The Washington University $720,353 on March 25, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Assistance Listing Project Grant R01DK141555). The award funds research to identify and elucidate the functioning of hypothalamic neural circuits that regulate energy balance and metabolism, with focus on obesity-associated metabolic diseases. The research targets a...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded $127,206 to The Washington University on April 5, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research investigates Prevotella copri-mediated effects of dietary glycan supplementation on microbial community and host metabolism in the context of treating childhood undernutrition. The work builds on clinical trial evidence that microbiota-directed complementary...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Washington University a Project Grant totaling $233,250 on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports research into the role of protein phosphatase 1K (PPM1K) in macrophage activation and metabolic disease. The research addresses a critical knowledge gap regarding branched chain amino...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Washington University $158,554 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds research investigating the role of ATP-sensitive potassium (KATP) channels in type 2 diabetes mellitus development. The project will examine mouse models of type 2 diabetes and human diabetic subjects to probe potential alterations in KATP channel activity...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Washington University $764,322 on August 10, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Project Grant R01DK144511). The award funds development of induced pluripotent stem cell (iPSC) modeling platforms to investigate partial lipodystrophy syndromes, a group of rare disorders characterized by regional loss of white adipose tissue that leads to insulin...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Washington University $277,506 on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), a K01 Mentored Career Development Award supporting research into cytoskeletal regulation of gut tube organogenesis and maturation of stem cell-derived islets. The award funds a career development training plan designed to transition the candidate to an independent...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The Washington University a Project Grant totaling $1,491,303 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) for the period September 5, 2025, through September 4, 2029. This award supports basic biomedical research investigating the molecular mechanisms that drive progression from acute kidney injury (AKI) to chronic kidney...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Washington University $388,750 on April 23, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the structural and functional mechanisms of podocin in glomerular membrane organization and kidney disease. The research applies detergent-free, vesicle-based cryo-electron microscopy to determine the full-length structure of podocin at near-atomic resolution...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Illinois $160,575 on July 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Project Grant K01DK147658). The award funds a three-year study of Medicaid alternative payment model (APM) implementation and evidence-based practice adoption in federally qualified health centers (FQHCs) to improve diabetes outcomes. The research addresses how FQHCs, which...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Boston Children's Hospital $831,433 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supporting research to redefine the biogeography and function of food proteins in human health and disease. The project establishes first principles of the food-host interactome by developing systematic approaches to map the transit, transformation, and tissue...
The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Washington University $663,077 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop and test implementation strategies for scaling the HEALTH (Healthy Eating and Active Living Taught at Home) obesity prevention intervention across Parents as Teachers (PAT) affiliates nationwide. The project uses implementation science, participatory systems science modeling, and adaptive strategy methods to refine and evaluate implementation strategy bundles designed to promote HEALTH adoption, implementation, and reach among PAT's network of parent educators. The study employs a sequential multiple assignment randomized trial design involving 627 PAT affiliates and aims to characterize the mechanisms supporting system-wide implementation of the intervention, which targets obesity prevention and healthy weight management among young adult women and mothers of young children. PAT, an evidence-based national home visiting organization, reaches 73,283 families through 4,300 parent educators across 920 affiliates and has committed to delivering HEALTH at scale, providing the infrastructure for this implementation research. Performance occurs at The Washington University in University City, Missouri, with a period of performance from September 1, 2026, through May 31, 2030. The award is classified as a Project Grant, an assistance type supporting extramural biomedical research that improves prevention, diagnosis, and treatment of diabetes, digestive, and kidney diseases.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $663.1k | 8/31/26 |