Project Grant R01DK144206
Award Date 8/10/26
Completion Date 4/30/30
Dollars Obligated $673K
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
New Orleans, LA 70112, USA
Similar Awards
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Administrators Of Tulane Educational Fund (Tulane University) $651,222 on August 10, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct basic research on molecular mechanisms driving metabolic dysfunction-associated steatohepatitis (MASH). The research investigates how ROBO1 (Roundabout Receptor 1), regulated by YAP and LHX2, promotes liver fibrosis in...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Tulane University $1,226,298 on September 24, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate epigenetic control of nephron progenitor cell lifespan in mice and humans. The research addresses the cessation of nephrogenesis at birth, which eliminates the opportunity to generate new nephrons following congenital or acquired loss of renal mass. The project...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded New York University $1,677,898 on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop fat and iron-corrected quantitative MRI T1 mapping as a non-invasive biomarker for evaluating chronic liver disease, particularly metabolic-associated steatohepatitis (MASH). The project addresses the clinical need for non-invasive assessment of liver pathology...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Tulane University $840,005 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the role of aryl hydrocarbon receptor (AHR) signaling in intestinal barrier function and inflammation during antiretroviral therapy-suppressed simian immunodeficiency virus infection. The research defines how gut AHR signaling preserves epithelial barrier...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Texas Health Science Center at Houston $154,332 on March 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the role of kynurenine-aryl hydrocarbon receptor signaling in cholestatic liver injury. The research examines how the kynurenine pathway and aryl hydrocarbon receptor activation regulate reactive oxygen species accumulation,...
- The National Institute of Diabetes and Digestive and Kidney Diseases, part of the Department of Health and Human Services National Institutes of Health, awarded $682,894 to St. Jude Children's Research Hospital Inc. on August 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to elucidate the role of LACTB2 in liver metabolic development. The research identifies critical metabolic regulators and pathways required for liver maturation during...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Baylor College of Medicine $200,000 on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, assistance type Project Grant). The funded research investigates how proteostatic stress—arising from fever-range hyperthermia, altered oxygen tension, and modulation of protein quality control pathways including chaperones, proteasome activity, autophagy, and...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded $814,500 to the University of Pittsburgh on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to fund research dissecting functional decompensation of end-stage liver disease and investigating the mechanism and impact of transcription factors on long-term functional reprogramming. The research examines how the transcription factor HNF4A—which controls...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the Board of Regents of the University of Nebraska $529,273 on April 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the MATRIN3-CAR-thrombin axis in hepatic inflammation and fibrosis. The research addresses metabolic dysfunction-associated steatotic liver disease (MASLD), which affects approximately 30 percent of U.S. adults and can progress to...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of California, Los Angeles $128,235 on September 13, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds research to discover mechanisms of metabolic dysfunction-associated steatotic liver disease (MASLD) through single nucleus RNA-sequencing analysis of cell-type and cellular subtypes in subcutaneous adipose tissue, visceral adipose...