Project Grant R01DK141458
- Federal Grant Award Summary The University of Michigan, through its Office of Research and Sponsored Projects, received a $151,040 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award, obligated on December 11, 2025, with an ultimate completion date of August 14, 2028, supports basic biomedical research investigating sex-specific effects and the...
- Federal Grant Award Summary The University of Michigan, through its Office of Research and Sponsored Projects, received a $728,801 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award, issued on September 24, 2025, with a completion date of June 30, 2030, supports research testing a novel weight navigation program designed to overcome multilevel...
- Federal Grant Award Summary The University of Michigan received a $129,306 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded on December 9, 2025, with completion targeted for June 30, 2028. The grant funds basic biomedical research to identify and characterize a novel neurocircuit that regulates stress-induced hyperglycemia (SIH)—the rapid...
- Summary of Federal Project Grant Award The University of Michigan received a $769,155 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), with an award date of September 12, 2025, and completion date of July 31, 2030. The grant funds the Michigan Diabetes Project, a research initiative designed to develop and evaluate a virtually administered,...
- Federal Grant Award Summary The University of Michigan received a $1,221,956 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective September 1, 2025, through June 30, 2030. This research initiative will investigate a novel signaling axis regulating gastric epithelial cell homeostasis and injury response by examining the relationship between Wnt and...
- Federal Grant Award Summary The University of Michigan's Regents, Office of Research and Sponsored Projects, received a $231,000 Project Grant award dated April 17, 2026, from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant funds research on remote loading of melanocortin and glucagon-like peptide-1 (GLP-1) peptides in polymers for obesity treatment, with a...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded the Regents of the University of Michigan a $779,978 Project Grant on September 6, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). This research initiative addresses critical health disparities in diabetes management by developing and testing adaptive intervention sequences designed to improve outcomes for individuals with...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded the Regents of the University of Michigan a $776,863 Project Grant on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct multi-ancestry whole genome sequencing analyses of metabolic dysfunction-associated steatotic liver disease (MASLD). The five-year research project, concluding August 31, 2030, aims...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded the Regents of the University of Michigan a $780,220 Project Grant on February 27, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop and optimize a scalable digital behavioral intervention for reducing Level 2 hypoglycemia in adults with Type 1 Diabetes (T1D). The project, which will conclude by January 31, 2030,...
- Federal Project Grant Award Summary The University of Michigan received a $651,082 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective June 15, 2026, with completion anticipated by March 31, 2030. The research investigates the reactivation of developmental signaling programs during human intestinal injury and repair, specifically examining...
The University of Michigan received a $645,154 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective July 1, 2026, through June 30, 2031. This research initiative will investigate the role of androgens in sex-specific metabolic inflammation (meta-inflammation) responses associated with obesity and related cardio-metabolic disease. The research team will conduct mechanistic studies examining how androgens directly stimulate inflammatory responses and lipid-associated macrophage programming differently between males and females in response to high-fat diet conditions, with the ultimate goal of identifying sex-specific risk factors and improving targeted, personalized treatment strategies for diabetes and cardiovascular disease. The project addresses a significant public health challenge by elucidating the biological mechanisms underlying sex differences in obesity-induced inflammation, which remains poorly understood despite strong links to cardio-metabolic complications. Through rigorous basic research utilizing animal models and comparative analysis of myelopoiesis and adipose tissue macrophage activation, the research will generate fundamental knowledge that may inform the development of sex-stratified clinical interventions and advance personalized medicine approaches for metabolic disease management.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $645.2k | 6/25/26 |