This $669,342 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will fund a longitudinal study to assess insulin vesicle functional capacity, beta cell mass, and pancreas volume in individuals at risk for and with recent onset type 1 diabetes. The study aims to utilize PET and MRI techniques to provide a comprehensive picture of multiple measures of beta cell function and mass over time, in order to increase understanding of the relationship between proposed imaging markers and pancreas architecture and function. The award will enable the primary grantee, Yale University, to conduct this research from March 2025 through February 2030.
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