This $464,446 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant is funding a multi-year research project conducted by the Veterans Medical Research Foundation of San Diego to investigate the mechanisms underlying acute kidney injury caused by mechanical ventilation in critically ill patients. The research aims to identify the physical changes in kidney glomerular and tubular function that contribute to decreased kidney filtration and sodium retention during mechanical ventilation, as well as the relationship between these functional changes and structural kidney injury. Ultimately, the goal is to uncover novel targets for future therapies to prevent acute kidney injury in mechanically ventilated patients, whose mortality rate exceeds 50% due to this complication. The award period is from May 15, 2024 to April 30, 2029.
Generated 3/4/25, 5:43 AM