Project Grant R01DC023948
- The National Institute on Deafness and Other Communication Disorders awarded The University of Chicago $451,000 on August 24, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to develop a native biochemical preparation of the mechanotransduction complex (METC) from cnidarian nematocytes as a model of vertebrate hair-cell function. The award funds research into the structural dynamics and functional mechanisms of the METC, the cellular machinery...
- The National Institute on Deafness and Other Communication Disorders awarded The Washington University $464,646 under Project Grant R01DC024001 on July 15, 2026, to investigate cortical mechanisms underlying hearing deficits in noisy environments following noise-induced hearing loss. The research employs longitudinal in vivo two-photon calcium imaging in awake mice to characterize responses of primary auditory cortex neurons—including glutamatergic principal neurons and inhibitory interneurons...
- The National Institute on Deafness and Other Communication Disorders awarded The Johns Hopkins University $194,270 on May 11, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to investigate the development of auditory thalamocortical circuits and how they are altered in cases of congenital deafness. The project will establish a foundational understanding of how the thalamus and auditory cortex develop and mature through sensory experience, with...
- The National Institute on Deafness and Other Communication Disorders awarded The Johns Hopkins University $654,879 on July 17, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to investigate cortical representations of electrical stimulation in cochlear implant recipients. The research elucidates fundamental neural coding and plasticity mechanisms responsible for cortical processing of cochlear implant signals. The project employs optical imaging and...
- The National Institute on Deafness and Other Communication Disorders awarded The University of Chicago $705,937 on May 1, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to investigate multiscale integration of inner ear vestibular signals from cellular dynamics to population coding. The research examines how Type I and Type II hair cells in the mammalian vestibular inner ear contribute to information processing and afferent neural encoding. The...
- The National Institute on Deafness and Other Communication Disorders awarded the University of Pittsburgh $664,448 on September 1, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The award funds investigation of how heterogeneous neural responses in auditory cortex and secondary motor cortex contribute to auditory learning and perception. The project combines large-scale neural recordings with optogenetic manipulations to examine how local auditory...
- The National Institute on Deafness and Other Communication Disorders awarded the University of Wisconsin - Madison $1,166,250 on September 16, 2025, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to investigate cortical population coding and network effects of cochlear implant stimulation during behavioral tasks. The research addresses gaps in understanding why cochlear implant outcomes vary significantly among users, despite over one million people...
- The National Institute on Deafness and Other Communication Disorders awarded New York University $135,972 on July 1, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to investigate neural computations underlying intensity perception across sensory systems. The award funds research combining behavioral measures and neural recordings to advance understanding of how intensity perception is encoded across unimodal and multimodal olfactory and auditory...
- The National Institute on Deafness and Other Communication Disorders awarded the University of Washington $490,487 on February 13, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to study spatial patterning in the zebrafish inner ear and its relevance to vestibular dysfunction in humans. The project investigates how hair cells in vestibular organs establish distinct central and peripheral regions with conserved functional and molecular identities...
- The National Institute on Deafness and Other Communication Disorders awarded The Washington University $647,082 on August 24, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to investigate mechanisms of hair cell vulnerability following sublethal cisplatin exposure. The research examines how cisplatin, a widely used cancer treatment, causes permanent hearing loss in patients years after treatment ends and sensitizes the cochlea to subsequent noise...
The National Institute on Deafness and Other Communication Disorders (NIDCD), part of the National Institutes of Health, awarded The Washington University $557,999 on September 1, 2026, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The award funds investigation of how inner hair cells in the cochlea encode sound frequency and intensity across a wide dynamic range. The research employs in vivo two-photon cochlear imaging integrated with single-cell optogenetics, auditory physiology, and inner ear drug and gene delivery to monitor and perturb individual inner hair cells while simultaneously measuring ensemble activity. Aim 1 characterizes population-level tuning properties of inner hair cells and compares these cellular features with neural tuning curves measured in the same animals, examining cell-by-cell response properties and correlated activity among inner hair cells to assess how functional ensembles shape frequency and intensity coding. Work is performed at Washington University in St. Louis, Missouri, with a period of performance from September 1, 2026, through August 31, 2031. The assistance type is a project grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $558.0k | 8/20/26 |