This federal Project Grant award, funded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports scientific research to characterize the transformation of odor responses from glomeruli to mitral and tufted cells in the olfactory system of awake animals. The $665,886 grant, awarded to New York University School of Medicine, will capitalize on recent technological advances to record neuronal activity using 2-photon calcium imaging and optogenetic pattern stimulation. The research aims to analyze the relationship between glomerular responses and mitral/tufted cell responses, elucidate the mechanisms underlying this transformation, and investigate the role of this transformation in concentration-invariant odor recognition. The proposed work will generate new insights into the principles of information processing in the peripheral olfactory system and develop tools to advance the study of olfactory function in mammals.
Generated 2/25/25, 3:29 AM