This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), will investigate the mechanisms behind balance dysfunction caused by Lassa virus infection. The $647,643 award, made on August 23, 2024, will be used by the University of Texas Medical Branch at Galveston to: 1) Characterize the vestibular histopathology and balance deficits in Lassa fever model mice over time, 2) Conduct in-depth vestibular behavioral testing in a Lassa virus surrogate mouse model, and 3) Determine the most effective treatment modalities, such as immunosuppressive agents or hyperbaric oxygen therapy, to improve balance outcomes. This research aims to elucidate the underlying causes of balance issues that can develop in Lassa fever survivors and inform the development of effective prevention and treatment strategies for viral infection-induced balance dysfunction.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $647.6k | 8/23/24 |