The University of Rochester received a $549,288 Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The funding will support research to investigate the neural circuits and feedback projections between the hippocampus and the main olfactory bulb that influence how odors are encoded and perceived in relation to cognitive and behavioral factors such as spatial awareness and anxiety. Using a combination of electrophysiology and behavioral measures, the project aims to determine what types of behaviorally-relevant information the hippocampal neurons transmit to the olfactory bulb, and how this affects chemosensory processing. The award has an initial period of performance from August 2024 through May 2029. Improved understanding of these circuits could provide critical insights into the connections between chemosensory function and neurological, neurodegenerative, and neuropsychiatric disorders.
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