Project Grant R01CA304933
- Federal Project Grant Award Summary The University of Illinois received a $123,526 Project Grant from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398), awarded on June 16, 2025, with completion targeted for December 15, 2026. This award supports research investigating the effects of ovulation on fallopian tube-derived tumorigenesis using a microfluidic organ-on-chip platform. The project delivers scientific research products focused on understanding...
- Federal Project Grant Award Summary The University of Illinois received a $573,470 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research program (CFDA 93.394) awarded on August 25, 2025, with a completion date of July 31, 2030. The grant supports the development of Resonance Enhanced Null-Deflection Infrared (RENDIR) spectroscopic imaging technology—an advanced atomic force microscopy (AFM) combined with infrared spectroscopy system designed to enable...
- Federal Grant Award Summary The National Cancer Institute awarded the University of Illinois a $386,279 Project Grant on July 10, 2025, under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to develop innovative immunotherapy screening capabilities. The grant funds the creation of a microfluidic device cassette and associated functional immune assay protocols designed to enable personalized immunotherapy screening directly on core needle biopsies from cancer patients. This...
- Grant Award Summary The National Cancer Institute awarded the University of Illinois at Urbana-Champaign $1,477,345 under the Cancer Centers Support Grants program (CFDA 93.397) for the Cancer Center at Illinois (CCIL), effective April 1, 2026 through March 31, 2029. This Basic Cancer Center support grant provides organizational infrastructure and resources to advance the CCIL's interdisciplinary cancer research mission through a "discovery-to-use" paradigm that integrates engineering,...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a $412,249 Project Grant under the Cancer Biology Research program (CFDA 93.396) to the University of Illinois, Chicago to support research on novel innate immune checkpoint receptors. The award, issued May 13, 2026, with completion targeted for April 30, 2027, funds investigative work aimed at identifying and characterizing vascular cell adhesion molecule-1 (VCAM-1) receptors on phagocytic cells that mediate immune...
- Federal Grant Award Summary The University of Chicago received a $372,628 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research program (CFDA 93.394) awarded on September 12, 2025, with a completion date of August 31, 2028. This award supports the development and advancement of spatiomolecular profiling technologies for human cancer research. Specifically, the project focuses on developing Array-Seq, a large-format spatially resolved transcriptomics...
- The University of Illinois received a $690,539 project grant award from the Defense Health Agency through the Military Medical Research and Development program (CFDA 12.420). The grant will fund research from August 1, 2023 through July 31, 2026 to investigate G0S2 as a master regulator of the local estrogenic environment during breast cancer progression and antiestrogen therapy. Through this award, the University will conduct scientific research that aims to transform healthcare for service...
- The University of Illinois was awarded a $719,550 Project Grant from the Defense Health Agency under the CFDA Program 12.420 - Military Medical Research and Development. The grant, with an April 1, 2024 award date and March 31, 2027 completion date, will support research on the TRKA-MLK3 axis as an actionable target in triple-negative breast cancer. The project aims to advance scientific understanding and develop new treatments related to this specific type of breast cancer, which is a key...
- Federal Grant Award Summary The University of Chicago received a $391,951 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2030. The award funds fundamental research to probe and target lysyl oxidase (LOX) enzymes and their role in cancer pathophysiology. The research focuses on understanding how protein post-translational modifications...
- Federal Project Grant Award Summary Cornell University's Office of Sponsored Programs received a $1,152,674 project grant award from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396) on August 11, 2025, with completion scheduled for July 31, 2030. This five-year research initiative, titled "The Integrated Mechanobiology and Glycobiology of Bone Metastasis," delivers fundamental cancer biology research aimed at understanding how bone mineral...
The University of Illinois received a $565,909 Project Grant award from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396), effective May 1, 2026 through April 30, 2031. The award funds research investigating engineered mineralized hydrogels as experimental systems to study microcalcifications in breast cancer. The project develops and utilizes novel, patented extracellular matrix-mimetic hydrogels that replicate the soft breast tumor microenvironment while incorporating distinct mineral compositions observed in breast cancer cases. The research aims to advance understanding of how microcalcification chemical composition—specifically distinguishing between benign calcium oxalate deposits and malignant calcium phosphate/hydroxyapatite formations—influences tumor growth, bone mimicry, and metastatic progression in the primary tumor microenvironment. This fundamental cancer biology research addresses a significant gap in knowledge regarding the relationship between microcalcifications and breast cancer aggressiveness. By providing improved experimental systems that accurately reflect in vivo microcalcification chemistry, the project is designed to support the development of early intervention strategies to prevent breast cancer progression and metastasis. The research is conducted at the University of Illinois Chicago campus and falls within the Cancer Biology Research program's focus on understanding cancer cell biology, tumor biology and metastasis mechanisms, with applications toward improved prevention, detection, and treatment approaches for neoplastic diseases.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $565.9k | 5/5/26 |