Project Grant R01CA300053
- Federal Project Grant Award Summary The National Cancer Institute (National Institutes of Health) awarded a $712,375 Project Grant to the University of California, Berkeley under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) on April 1, 2026, with a completion date of March 31, 2031. The award funds development of the ADAPT PRO system, a digitally programmable radiofrequency (RF) system designed to enable Magnetic Resonance Imaging (MRI) of any nucleus beyond the standard...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a $700,838 Project Grant to The Regents of the University of California, San Francisco under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) for the period April 1, 2026 through March 31, 2031. This award supports research and development of an advanced imaging and treatment planning system designed to optimize Stereotactic Body Radiation Therapy (SBRT) for liver cancer patients while minimizing...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded $185,760.00 to The Regents of the University of California, San Francisco under the Cancer Research Manpower program (CFDA 93.398) on July 7, 2025. This Project Grant funds research aimed at enhancing treatment outcomes for metastatic castration-resistant prostate cancer (MCRPC) through the development of novel tumor-targeted combination therapy. The primary research deliverable involves creating a single...
- Federal Project Grant Award Summary The National Cancer Institute awarded a $382,449 Project Grant to the University of California, Los Angeles under the Cancer Detection and Diagnosis Research program (CFDA 93.394) on July 16, 2025, with completion targeted for June 30, 2027. This research project develops and validates advanced dual-nuclei magnetic resonance imaging (MRI) techniques to non-invasively differentiate between recurrent brain metastases (RBM) and radiation-induced necrosis (RN)...
- Federal Grant Award Summary The National Cancer Institute awarded a $409,141 Project Grant to the University of California, Davis, effective June 1, 2026, through May 31, 2028, under the Cancer Detection and Diagnosis Research Program (CFDA 93.394). The grant supports research and development of perfusion computed tomography (CT) imaging technology as an alternative diagnostic tool for liver radioembolization treatment planning. The project aims to validate contrast-enhanced perfusion CT as a...
- Federal Grant Award Summary The National Cancer Institute awarded a $648,049 Project Grant to the University of California, Irvine, under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) to develop protoacoustic imaging technology for real-time Bragg peak localization during proton therapy. The award, effective April 2, 2026, through March 31, 2031, will deliver a dual-modality protoacoustic/ultrasound imaging system designed to precisely monitor radiation dose delivery and...
- Federal Project Grant Award Summary The University of California, Davis received a $149,394 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research program (CFDA 93.394) effective August 1, 2025 through July 31, 2030. This award supports research in targeted radiotheranostics—the development and clinical translation of diagnostic and therapeutic radiopharmaceuticals that enable integrated imaging and treatment of cancer. The research encompasses the...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded University of California, Davis a $551,328 Project Grant under the Cancer Treatment Research program (CFDA 93.395) effective April 1, 2026, with a completion date of March 31, 2031. This five-year research initiative focuses on dissecting the role of Carnitine Palmitoyltransferase 1C (CPT1C) in advanced prostate cancer, specifically neuroendocrine prostate cancer (NEPC), an aggressive subtype that emerges from...
- Federal Grant Award Summary The University of California, San Francisco (UCSF) received a $783,538 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) for the period May 1, 2025 through April 30, 2028. The award funds research to develop and validate "4D Tissue Fabrication," an innovative approach designed to improve the reproducibility and complexity of patient-derived organoids (PDOs) for drug testing and disease...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded New York University School of Medicine a $681,215 Project Grant effective September 1, 2025, through August 31, 2030, under the Cancer Detection and Diagnosis Research program (CFDA 93.394). The award supports development of artificial intelligence (AI)-enabled point-of-care magnetic resonance (MR) imaging technology for clinically significant prostate cancer detection. The research addresses limitations of the...
The National Cancer Institute (NCI) awarded The Regents of the University of California, San Francisco a Project Grant of $679,290 under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) for the period April 1, 2026 through March 31, 2031. The project focuses on translating novel hyperpolarized (HP) carbon-13 dual-agent magnetic resonance imaging (MRI) techniques to improve prostate cancer detection and biopsy guidance. The research aims to develop and validate quantitative metabolic biomarkers—specifically HP pyruvate-to-lactate conversion rates and HP urea MR measurements—that can reliably identify aggressive prostate cancer with approximately 10 times higher sensitivity than current multiparametric MRI approaches, thereby addressing the significant clinical need to improve patient stratification and treatment planning. The deliverables include the development and clinical translation of non-radioactive, metabolically-inert imaging probes using stable-isotope technology to provide enhanced tissue perfusion and metabolic information that correlates with prostate cancer aggressiveness. This research addresses documented limitations in current prostate imaging practices, including the substantial inter-reader variability associated with Prostate Imaging Reporting and Data System (PI-RADS) scoring and the missed diagnosis of clinically significant cancer in approximately 20 percent of patients with negative multiparametric MRI examinations. The project is designed to generate improved quantitative diagnostic tools to guide clinical decision-making for biopsy procedures and focal therapy planning in intermediate-risk prostate cancer patients.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $679.3k | 3/20/26 |