Project Grant R01CA297324
- This Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) provides $233,411 to Pennsylvania State University's Milton S. Hershey Medical Center to conduct a randomized controlled trial (RCT) evaluating a narrative communication intervention delivered through digital and mobile technology. The goal is to understand how narrative messaging can influence HPV vaccine decision-making and increase HPV vaccine initiation rates among parents of...
- The National Cancer Institute (NCI), through the Cancer Research Manpower (CFDA 93.398) federal grant program, awarded Northwestern University a $191,700 Project Grant to develop and test a culturally-relevant digital health intervention targeting HPV vaccination among U.S. Vietnamese individuals. The project, titled "Applying the Multiphase Optimization Strategy to Develop and Test a Culturally-Relevant Digital Health Intervention Targeting HPV Vaccination Among U.S. Vietnamese", will...
- This Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) provides $630,506 to The Johns Hopkins University to develop and test a therapeutic vaccine against cervical cancer associated with variants of the human papillomavirus type 16 (HPV16). The primary goals are to: 1) characterize how different HPV16 variants evade immune system detection, 2) study the growth and tumor microenvironment of spontaneous cervical/vaginal cancers driven by HPV16...
- This Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) provides $3,277,279 to Tufts Medical Center Parent, Inc. (doing business as Tufts Medical Center) to develop and evaluate English and Spanish smartphone Embodied Conversational Agents (ECAs) to improve follow-up rates for patients with abnormal cervical cancer screening results. The ECAs will provide follow-up recommendations, motivational interviewing, and facilitate communication...
- The National Cancer Institute (NCI) awarded a Project Grant (CFDA 93.395 - Cancer Treatment Research) to Ampedrna Biosciences LLC in the amount of $398,823 to develop a highly immunogenic mini-circular RNA (mcrRNA) therapeutic cancer vaccine for human papillomavirus (HPV)-related cancers. The goal is to create an off-the-shelf or personalized vaccine that can elicit robust and durable T cell responses to target HPV E6 and E7 antigens, which are known to drive HPV-induced cancers. The proposed...
- This Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) provides $544,768 to the University of New Mexico to conduct research focused on understanding the fundamental biological mechanisms of human papillomavirus (HPV)-induced tumors and precancerous lesions. The award aims to elucidate how inhibition of the MEK/ERK signaling pathway can lead to regression of HPV-driven tumors, with the goal of advancing scientific knowledge that can enable improved...
- This Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) provides $371,161 to develop advanced AI-based risk models for cervical cancer screening in low-resource settings. The project aims to leverage time-series imaging data and self-supervised learning to enhance the diagnostic accuracy of automated visual evaluation (AVE) models. The goal is to create a comprehensive risk stratification system that combines imaging data, HPV...
- This Project Grant award for $705,322.00, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), aims to develop and test an AI-based chatbot intervention to promote HIV pre-exposure prophylaxis (PrEP) uptake among men who have sex with men (MSM) in Ending the HIV Epidemic (EHE) jurisdictions. The project, awarded to The Miriam Hospital, a division of Lifespan located in Rhode Island, will involve tailoring, refining, and...
- This $544,250 federal Project Grant awarded by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) to the University of Nebraska Medical Center (UNMC) will support research to investigate the immune drivers of persistent oncogenic infections, such as oral human papillomavirus (HPV), and their progression to cancer among people living with HIV. The overarching goal is to improve prevention, early detection, and treatment outcomes for infection-related cancers in this high-risk...
- The federal Project Grant award of $397,772 was provided by the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research program) to Harvard T.H. Chan School of Public Health. The grant will fund the development of computational methods for profiling the cancer virome and analyzing microbial strain genetics from shotgun metagenomes and metatranscriptomes. This research aims to address key knowledge gaps in understanding the role of viruses and microbial strain variations...
This Project Grant award from the National Cancer Institute's Cancer Cause and Prevention Research program (CFDA 93.393) aims to support informed decision-making about human papillomavirus (HPV) vaccination among parents of adolescents in the United States. The $2,834,092 award, made on August 15, 2025, will fund the development and evaluation of an AI-powered chatbot that delivers personalized, evidence-based messages to address individual concerns and communication preferences regarding HPV vaccination. The project, led by the University of Maryland, College Park, will refine the chatbot through user-centered design and assess its effectiveness in improving vaccination attitudes, intentions, and uptake through two randomized controlled trials. This innovative, scalable approach has the potential to enhance vaccine communication and inform broader applications of AI tools in public health.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.8m | 8/14/25 |