This Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) provides $1,003,164 to Yale University to evaluate the feasibility and efficacy of a virtual in-person cognitive-behavioral therapy (CBT) and an app-based CBT intervention for vaping cessation among youth. The project aims to 1) examine the efficacy of the "KICK-NIC!" smartphone app, which uses multimedia-rich and interactive CBT to teach coping skills for...
This Project Grant award from the National Cancer Institute (NCI), under the federal Cancer Cause and Prevention Research program (CFDA 93.393), provides $687,995 to Yale University to conduct a randomized clinical trial investigating the efficacy of varenicline for e-cigarette cessation. The 5-year project aims to: 1) Compare quit rates between varenicline and placebo among adults who use e-cigarettes exclusively, 2) Identify predictors and moderators of treatment response, and 3) Explore...
This federal Project Grant award from the National Cancer Institute (NCI), under the Cancer Cause and Prevention Research (CFDA 93.393) program, will fund the development and pilot testing of an AI-enhanced smartphone app-based intervention for adolescent electronic cigarette (e-cigarette) cessation. The $257,415 award will support the creation of a scalable, AI-powered app that can deliver personalized cessation content and real-time support to adolescents struggling with e-cigarette use. The...
This federal Project Grant award of $565,181.00 from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393) aims to identify key features of e-cigarette-related social media posts that drive high user engagement. The University of Rochester, the awardee, will use advanced artificial intelligence and statistical modeling techniques to characterize Twitter, Instagram, TikTok, and YouTube posts related to e-cigarettes and vaping. The goal is to...
This $310,319 federal Project Grant award from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research (CFDA 93.393) program supports a study to develop a motivation-based typology of adolescent e-cigarette users. The goal is to use this typology to inform the development of tailored cognitive-behavioral e-cigarette cessation interventions for adolescents. The University of Louisville, a public research university, will conduct a mixed-methods study with 1,200 high...
The National Cancer Institute (NCI) awarded a $692,872 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) to The Regents of the University of California, San Francisco (UCSF) to develop and evaluate a scalable social media-based vaping cessation program for adolescents. The "Quit the Hit Toolkit" (QTHT) program will be implemented through community partner organizations in a randomized controlled trial to assess its effectiveness in helping adolescents...
This federal Project Grant award from the National Cancer Institute (NCI), funded under the Cancer Cause and Prevention Research program (CFDA 93.393), provides $619,175 to the Medical University of South Carolina (MUSC) to conduct a hybrid effectiveness-implementation trial evaluating the use of e-cigarettes as a harm reduction approach for oncology outpatients who smoke but refuse traditional tobacco treatment. The key products and services to be delivered include: 1) Directly comparing...
This Project Grant award from the National Cancer Institute (NCI), under the Cancer Cause and Prevention Research program (CFDA 93.393), will fund a study to evaluate a remote, young adult lay-counselor delivered behavioral and digital intervention called "QuitVaping" to promote vaping cessation and prevent escalation of tobacco use among adolescents. The $1,698,536 award to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), will enroll 300...
This $610,092 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) is designed to develop and test a hybrid substance use prevention program for upper elementary school students. The program will utilize a combination of online e-learning modules and traditional classroom sessions to teach students about the harms of vaping and the importance of safe prescription medication use. It will also focus on enhancing...
This Project Grant award of $3,002,492 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund research to assess the impact of e-cigarette use on pulmonary function in young healthy adults. The research will use an advanced imaging technique called hyperpolarized xenon-129 MRI (HXEMRI) to quantify early physiological changes in the lungs of e-cigarette users compared to non-users. The project will also evaluate the ability of a...