Project Grant R01CA291888

Award Date 7/1/24
Completion Date 8/31/29
Dollars Obligated $1.1M
Federal Grant Program
93.395
Assistance Type
Project Grant
Place of Performance
Durham, NC 27710, USA
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This $578,467 Project Grant award from the National Cancer Institute (CFDA 93.395 Cancer Treatment Research) to Duke University is for a randomized controlled trial testing the efficacy of a telehealth-delivered psychosocial intervention called ENGAGE. The intervention aims to decrease symptom interference (pain, fatigue, distress) and improve quality of life in patients with advanced cancer receiving care in medically underserved areas. The 5-year study will randomize 190 patients to receive...
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The National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) awarded Duke University a Project Grant totaling $1,123,468 to conduct a randomized controlled trial of a hybrid-delivered cognitive behavioral symptom management and activity coaching intervention for hematopoietic stem cell transplant patients. The goal is to use mobile health technology to enable these patients to effectively cope with symptoms like fatigue, pain, and distress, in order to improve their physical disability and engagement in physical activity. The 5-year research project will test the efficacy of the "STEP UP" intervention, which combines in-person and video-delivered symptom coping skills training and activity coaching sessions, along with a mobile app and wearable activity trackers to provide real-time personalized feedback. The research aims to demonstrate how this hybrid intervention can concurrently decrease symptom burden and increase physical activity to enhance patient outcomes following stem cell transplantation.

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