The National Cancer Institute (NCI) awarded Virginia Commonwealth University (VCU) a Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to conduct a randomized controlled trial of a tailored exercise intervention for breast cancer survivors receiving anthracycline-based chemotherapy. The 5-year, $671,757 award will assess whether the exercise program can preserve exercise capacity, left ventricular function, and health-related quality of life, while reducing fatigue in this patient population. The project will utilize advanced MRI and cardiopulmonary exercise testing methods to provide mechanistic insights into how physical activity during cancer treatment helps preserve exercise capacity. It will also examine the impact of dietary fatty acid intake on exercise capacity. This study aims to establish a new paradigm for more effective and patient-centered care to improve long-term outcomes for breast cancer survivors.
Generated 3/4/25, 7:42 AM