Project Grant R01AT013603
- This $4,899,748 federal Project Grant was awarded on September 19, 2025 by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, under the Drug Use and Addiction Research Programs (CFDA 93.279). The grant supports research to elucidate the biopsychosocial mechanisms underlying inter-individual differences in movement-evoked pain and functional impairment in knee osteoarthritis patients. Key activities include using concurrent ambulatory brain...
- This federal Project Grant award in the amount of $5,057,591 was provided by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The purpose of the award is to conduct a comprehensive, prospective observational study with 2,400 emergency department patients seeking care for acute pain. The study aims to: 1) characterize clinically-informed pain phenotypes, 2)...
- This Cooperative Agreement award of $1,614,289.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop a novel composite digital endpoint to integrate measurements of pain and gait patterns in individuals with knee osteoarthritis (OA). The project, which runs from August 1, 2025 to July 31, 2027, will employ a patient-centered approach to select and validate the technology, conduct analytical...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), is funded under the Drug Use and Addiction Research Programs (CFDA 93.279). The $1,098,640 grant, awarded on September 18, 2025, supports a longitudinal research project titled "Modeling Inter-Individual Differences to Address Pain of Sickle Cell Disease (MIDAS)" at the University of Texas at Arlington (UTA). The project aims to collect...
- This Project Grant award was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The $226,530 award will support a research project at the University of California, San Francisco (UCSF) focused on using brain stimulation to identify and test network biomarkers for chronic pain relief. The project aims to leverage advanced functional MRI,...
- This federal Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279), is focused on developing novel methods for selectively stimulating nociceptors (pain receptors) and measuring the brain's nociceptive-specific response in both healthy individuals and those with the chronic pain condition fibromyalgia. The $2,314,276 award to Emory University will fund the creation of a new...
- This $4,039,366 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), will support a research project titled "A Fully Humanized Functional Genomic Screen to Identify and Validate Pain Therapeutic Targets" under the NIH's Drug Use and Addiction Research Programs (CFDA 93.279). The project will leverage innovative CRISPR-based screening and human dorsal root ganglion (DRG) transcriptomic data to...
- This $408,000 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program supports research to provide a comprehensive EEG profile of the cortical activity underlying the cognitive processing of the sensory-discriminative and affective-motivational dimensions of osteoarthritis knee pain. The research, conducted by Tarleton State University,...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), awarded a $1,955,201 Cooperative Agreement to Cincinnati Children's Hospital Medical Center under the NIH Drug Use and Addiction Research Programs (CFDA 93.279). The 5-year award, effective September 19, 2025 through July 31, 2030, will support research to better understand the biopsychosocial determinants of pediatric-onset chronic musculoskeletal pain. The research will...
- This Project Grant award, provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to develop computational tools to accurately predict and interpret different patterns of knee pain in patients with osteoarthritis. The $348,680 award, with a period of performance from Sep 26, 2024 to Aug 31, 2026, will enable researchers at the University of Arizona to: 1) Adapt a...
This Project Grant award of $4,649,740 from the National Institute of Neurological Disorders and Stroke (part of the National Institutes of Health) under the Drug Use and Addiction Research Programs (CFDA 93.279) is funding research to develop network-based models for understanding inter-individual differences in the progression of chronic musculoskeletal pain, using knee osteoarthritis as a case study. The research aims to: 1) Use natural language processing to annotate patient narratives and develop network representations of their lived pain experience; 2) Leverage home-based video analysis to generate network models of patient functional status; and 3) Examine transitions in pain, function, and psychosocial factors over time to identify key determinants of clinical trajectories. The award has a performance period from August 15, 2025 to July 31, 2029 and is being led by George Mason University, with support from its affiliated non-profit organization The George Mason University Instructional Foundation, Inc.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $4.6m | 8/14/25 |