The National Center for Complementary and Integrative Health (NCCIH) awarded a $492,436 Project Grant (CFDA 93.213 - Research and Training in Complementary and Integrative Health) to Florida International University (FIU) to conduct a randomized clinical trial evaluating the efficacy of a remotely delivered Tai Chi/Qigong (TCQ) intervention in improving depressive symptoms among older adults living with HIV. The 5-year project aims to determine the direct and indirect effects of the TCQ intervention, as well as examine potential moderating effects of gender. The study will recruit 326 participants nationwide, with assessments conducted via videoconferencing or phone. Blood samples will also be collected to analyze viral load and inflammation. The findings could inform the development of accessible, non-pharmacological interventions to manage depression in this population.