Project Grant R01AR086872
- Federal Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $172,034 Project Grant to the University of Nebraska Medical Center on August 15, 2025, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). This research initiative, with a completion date of June 30, 2030, focuses on identifying molecular and epidemiologic determinants of myocardial dysfunction and heart failure (HF) in patients with...
- Federal Grant Award Summary The University of California, San Francisco received a $1,031,877 Project Grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), awarded July 1, 2025, with a completion date of April 30, 2030. This research initiative, titled "Endogenous Retroviruses in Autoimmunity: T Cell Repertoire, Tolerance, and Disease," will deliver biomedical...
- Federal Project Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded $382,537 to The Regents of the University of Colorado-Denver on August 1, 2025, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) for a five-year research project extending through July 31, 2030. The primary deliverable is basic and translational research investigating the pathogenic roles of Granzyme K-expressing CD8 T cells in...
- Federal Project Grant Award Summary Brigham & Women's Hospital Inc. received a $529,616 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), effective June 1, 2025, with a completion date of May 31, 2030. The award funds research to define the role of Notch-driven fibrogenesis in treatment failure in rheumatoid arthritis (RA), specifically investigating...
- Federal Grant Award Summary The University of California, Los Angeles received a $366,639 Project Grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), awarded September 5, 2025, with completion targeted for August 31, 2029. This award funds research to understand mechanisms driving poor outcomes in women with dermatomyositis (DM), a rare autoimmune disease that...
- Federal Grant Award Summary The University of Oklahoma Health Sciences Center received a $700,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded on September 4, 2025, with a completion date of August 31, 2029. This award funds investigator-initiated research to advance understanding of ARID3A (A+T-Rich Interaction Domain Protein 3A) function in autoimmune B cells and its role in...
- Federal Grant Award Summary Massachusetts General Hospital received a $165,240 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), effective June 1, 2026 through May 31, 2031. The award funds research to unravel shared and unique mechanisms of autoimmunity using systems immunology approaches, with a particular focus on regulatory T (Treg) cell...
- Federal Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a Project Grant totaling $180,144 to The Regents of the University of California, San Francisco under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award, effective June 1, 2026, through April 30, 2031, supports investigator-initiated basic science research led by Dr. Taylor LaFlam examining the role of P2RY8, a G-protein-coupled receptor,...
- Federal Project Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $170,964 Project Grant to Yale University on May 15, 2026, under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). This five-year career development award supports research investigating the mechanisms by which retroelements contribute to systemic lupus erythematosus (SLE) autoimmunity. The research will generate scientific outputs...
- Federal Grant Award Summary This $172,560 Project Grant, awarded June 1, 2026, through May 31, 2031, by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports translational research investigating the role of SAP (SLAM-associated protein) positive T cells in lupus nephritis (LN). The research aims to elucidate the immune mechanisms driving tubulointerstitial inflammation...
The University of Houston System received a $667,276 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), effective May 20, 2026, with completion anticipated by April 30, 2031. The award funds a research investigation into the genetic and environmental triggers of systemic autoimmune rheumatic diseases (SARDs), including rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, and systemic sclerosis. The research deliverables include identification of genetic loci, environmental exposures, and gene-by-environment interactions associated with the development of anti-nuclear autoantibodies (ANAs) and subsequent disease onset through analysis of prospective cohort data from the Nurses' Health Study and Nurses' Health Study II cohorts. The project employs comprehensive proteomics analysis and immunoexposome array screening of plasma samples at baseline and 10-year follow-up to characterize molecular pathways and protein modules underlying early-phase autoimmunity in SARDs. Research outputs will identify the genetic, environmental, and interactive factors operative at two critical stages of SARD development—initial ANA emergence and subsequent disease manifestation—with the goal of informing prevention and treatment strategies for these chronic, debilitating diseases affecting over 30 million people worldwide.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $667.3k | 5/22/26 |