Project Grant R01AR086297
- This $224,100 federal Project Grant award, funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will support research to identify epigenetic factors that control the longevity of epidermal stem cells in adult skin. The project aims to elucidate the functional role of epigenetic regulators and their corresponding histone modifications in maintaining the longevity of hair...
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) provides $355,938 to Yale University to study the signaling dynamics that coordinate stem cell behaviors during tissue regeneration. The research aims to define the dynamics of epithelial ERK and mesenchymal TGFβ signaling and assess their functional impact on regenerative processes in the hair...
- This federal Project Grant award in the amount of $370,494 was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant supports research at Temple University to study the molecular mechanisms underlying post-inflammatory hyperpigmentation (PIH), a common skin condition characterized by increased pigmentation following inflammation or injury, particularly in...
- This $250,396 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will support research to identify differences in DNA regulatory elements that control gene expression in skin cells from individuals of different ancestral backgrounds. The research team at the Icahn School of Medicine at Mount Sinai will utilize advanced genomic techniques, including...
- This Project Grant award of $384,250 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research at the University of Alabama at Birmingham (UAB) to elucidate the role of PD-1/PD-L1 signaling in regulating interactions between immune cells and melanocyte stem cells. The project aims to decipher how PD-L1 enables crosstalk between melanocyte stem cells and neighboring immune cells to regulate immune privilege,...
- This federal Project Grant award, valued at $1,826,181.00 and effective from September 1, 2025 to August 31, 2028, was issued by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research grant program (CFDA 93.846). The grant aims to comprehensively understand the contribution of Langerhans cells, resident cells in the epidermis, to chronic itch associated with various skin and systemic diseases. The research...
- This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) provides $198,782 to Duke University to develop a platform that leverages 3D human reconstructed epidermis (RHE) cultures to investigate interactions between the skin microbiome and skin cell populations. The goal is to enable the investigation of host-microbe interactions at a large scale by knocking out human genes...
- This Project Grant award, totaling $176,148.00 and effective from April 1, 2025 to March 31, 2030, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846). The funding supports a research project led by Dr. Maxime Kinet at the University of California, San Francisco (UCSF) that aims to elucidate the mechanisms by which PI16-expressing fibroblasts, a...
- This federal Project Grant award of $129,035 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) supports a 5-year research training program. The award aims to advance the principal investigator's expertise in centrosome, cytoskeletal, and keratinocyte biology, with a focus on understanding the role of the centrosomal protein CEP43 in maintaining epidermal integrity and its...
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) will support research to characterize hematopoietic stem cell (HSC) impairment in a mouse model of systemic lupus erythematosus (SLE)-like disease. The $216,113 award to New York University School of Medicine will be used to test the hypothesis that SLE-like disease impairs HSC activity, potentially...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to understand the plasticity of melanocyte stem cells (MCSCs) and mature melanocytes in adult hair follicles. The $1,917,396 award to New York University School of Medicine will support live-imaging techniques to delineate the fate decision process of MCSCs, from partial differentiation to reversion to a stem cell state or full maturation. This research seeks to advance the understanding of this newly discovered MCSC plasticity and its implications for hair pigmentation, skin depigmentation, and melanoma. The project period is from Sep 1, 2025 to Aug 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.9m | 8/4/25 |