Project Grant R01AI195471
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Utah $743,752 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, through July 31, 2030. This five-year Project Grant funds investigator-initiated research examining the epigenetic programming of CD4+ helper T cells during chronic viral infection. The research will investigate how persistent antigen stimulation and...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Utah $625,348 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 3, 2025, for a project extending through June 30, 2030. This Project Grant funds basic immunological research investigating the gene regulatory network governing memory B cell and long-lived plasma cell differentiation. The research aims to define the role of Nuclear Factor Kappa B...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Utah $423,500 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 17, 2025, with a completion date of June 30, 2027. This R21 project grant supports biomedical research investigating the role of invariant Natural Killer T (iNKT) cells in Plasmodium-induced cerebral malaria pathogenesis. The primary research deliverables include scientific...
- Federal Grant Award Summary The University of Utah's Office of Sponsored Projects received a $3.08 million Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2029. This award supports investigator-initiated biomedical research examining the T cell receptor (TCR)-dependent and epigenetic mechanisms that govern CD4+ T cell responses to influenza infection...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Utah $423,500 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period extending from July 1, 2025 through June 30, 2027. This R21 Project Grant supports the development and evaluation of a novel chimeric antigen receptor T regulatory cell (CAR TREG) therapeutic design that targets programmed death-1 (PD-1) to enhance...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $463,676 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Maryland, Baltimore on August 7, 2025, with a completion date of July 31, 2030. This research project delivers comprehensive scientific investigation into the mechanisms of Fc-mediated effector functions in response to viral surface proteins, with particular emphasis on...
- Federal Grant Award Summary The University of Utah received a $423,500 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 22, 2025, with a completion date of June 30, 2027. The award supports research and development activities focused on PD-1 BIKE (Bispecific Killer Cell Engagers), a targeted therapeutic approach for treating autoimmune diseases through selective...
- Federal Project Grant Award Summary Utah State University received a $344,093 Project Grant award dated August 15, 2025, from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop a single-dose, long-lasting live-attenuated chimeric vaccine candidate against Kyasanur Forest Disease Virus (KFDV). The project, scheduled for completion by July 31, 2030, leverages the university's established vaccine...
- Federal Project Grant Award Summary The University of Utah's Office of Sponsored Projects received a $423,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 1, 2026 through January 31, 2028. This award funds investigator-initiated biomedical research examining the role of cholesterol metabolism in regulatory T cell (Treg) function and autoimmune disease. The research...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Wisconsin–Madison a Project Grant of $422,814 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 25, 2025, with a completion date of May 31, 2027. The award funds the development and application of adversarial machine learning methods to predict viral spillover risk—specifically, to identify which animal viruses are likely to infect humans and...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Utah a Project Grant of $481,520 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 20, 2026, with completion targeted for January 31, 2031. This research initiative investigates the molecular evolution of viral entry receptor usage in zoonotic betacoronaviruses, specifically examining SARS-CoV-2, MERS-CoV, and HKU1 alongside their animal reservoir variants in bats and rodents. The project delivers scientific research products including phylogenetic surveys of diverse animal coronavirus strains, high-throughput mutagenesis screening data mapping evolutionary and genetic mechanisms of receptor-binding transitions, and large-scale genotype-phenotype maps characterizing viral receptor-use mechanisms. The research outputs are designed to inform computational models for assessing viral zoonotic risk and guide the development of broad-spectrum antibody and vaccine therapeutics for pandemic preparedness. By elucidating the evolutionary forces enabling animal viruses to acquire human spillover traits through long-term host-virus dynamics, this project advances scientific understanding of cross-species transmission mechanisms and contributes to foundational knowledge supporting public health preparedness against emerging infectious diseases. The five-year project period aligns with the NIAID competitive research grant program framework supporting investigator-initiated biomedical research addressing critical infectious disease challenges.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $481.5k | 2/19/26 |