Project Grant R01AI193642
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Benaroya Research Institute At Virginia Mason a Project Grant totaling $2,684,352 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 20, 2026. This award supports advanced biomedical research investigating epitope-specific CD4+ T cell responses in at-risk individuals prior to the clinical onset of Type 1 Diabetes (T1D). The research will characterize...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $489,500 to the Benaroya Research Institute at Virginia Mason under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 20, 2026, with a completion date of January 31, 2028. This project grant funds biomedical research to identify and validate molecular mechanisms that inhibit central nervous system (CNS) resident memory T cells (TRM) driving neuroinflammation in...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $496,344 to the Benaroya Research Institute at Virginia Mason under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 19, 2026, with completion targeted for January 31, 2028. This Project Grant funds biomedical research investigating the DYRK1A-GP130 (dual-specificity tyrosine phosphorylation-regulated kinase 1A and glycoprotein 130) axis and its role in...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Benaroya Research Institute at Virginia Mason a Project Grant of $1,385,524 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 22, 2025, with a completion date of June 30, 2030. This award funds biomedical research focused on characterizing and targeting CD4+ tissue resident memory (TRM) T cells in experimental autoimmune encephalomyelitis (EAE), an animal model...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Benaroya Research Institute at Virginia Mason a $267,000 Project Grant on June 11, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a 24-month research investigation concluding May 31, 2028. The research deliverables encompass a comprehensive immunological characterization study examining how the therapeutic monoclonal antibody risankizumab...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $886,942 to the Benaroya Research Institute at Virginia Mason on June 17, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This Project Grant supports investigator-initiated biomedical research designed to elucidate the mechanisms underlying commensal-specific CD8+ T cell differentiation, regulation, and dysregulation in the intestinal epithelium. The research...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $429,000 Project Grant to the University of Colorado-Denver under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 3, 2025, with a completion date of June 30, 2027. This research project delivers investigative services focused on understanding the pathogenic mechanisms of Type 1 Diabetes (T1D), specifically examining the role of pH levels in insulin-producing...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Regents of the University of Colorado-Denver $634,984 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 10, 2025, for a project extending through June 30, 2030. This Project Grant funds investigator-initiated biomedical research aimed at uncovering the role of BND2 cells in Type 1 Diabetes (T1D) autoimmunity. The primary deliverables include scientific research...
- Federal Grant Award Summary Award Details: The National Institute of Allergy and Infectious Diseases (NIAID) awarded Tufts University School of Medicine a Project Grant totaling $1,294,374 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 3, 2025, with a completion date of June 30, 2030. Research Scope: This award funds investigation into the role of heme synthesis in controlling regulatory T cell (Treg) fitness and function, with the objective of developing...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded J. David Gladstone Institutes a $3.6 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 6, 2026, with completion targeted for January 31, 2030. This award funds research to elucidate the transcriptional and post-transcriptional regulatory networks governing regulatory T cell (Treg) identity and stability. The research employs CRISPR...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded $894,183 to the Benaroya Research Institute at Virginia Mason on June 11, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a five-year research project concluding May 31, 2031. The project, titled "Exploring In Vivo Treg Function in T1D Through the Lens of Expanded Tregs," delivers biomedical research services focused on understanding how regulatory T cells (Treg) function in type 1 diabetes (T1D), an autoimmune disease characterized by destruction of pancreatic islet beta cells. The research leverages existing primary human samples from the Sanford T-REX clinical trial to investigate the relationship between Treg proliferative capacity, metabolic state, and clinical outcomes in T1D patients treated with polyclonal autologous in vitro expanded Treg therapy. The project delivers investigator-initiated basic and translational research services aimed at characterizing intrinsic features of individual Treg cells that contribute to in vitro expansion capacity and subsequent in vivo suppressive function. Research activities include analysis of Treg gene signatures, phenotypic and transcriptional profiling, metabolic characterization, and examination of homing potential—products intended to advance scientific understanding of autoimmune disease regulation and inform development of improved therapeutic approaches for T1D management.Federal Project Grant Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $894.2k | 6/12/26 |