This Project Grant award of $1,211,704.00 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund comprehensive studies to elucidate the pathogenesis of severe dengue disease during primary infections. The research aims to determine differences in innate, antibody, and T-cell immune responses between severe primary and secondary dengue infections. The grant will leverage state-of-the-art tools and...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $318,085 to support research on the role of antibodies in controlling virus infections through Fc-dependent mechanisms such as antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytolysis (CDC). The research aims to elucidate the...
This federal Project Grant award for $246,623.00 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research at New York University School of Medicine to study the molecular control of tolerogenic dendritic cell function. The research aims to characterize the dendritic cell subset responsible for maintaining T cell tolerance, including investigating aberrant cytokine...
The federal Project Grant award R01AI186945 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) for $625,348 with a period of performance from Jul 3, 2025 to Jun 30, 2030. The grant supports research at the University of Utah to define the role of the NF-kB signaling network in regulating affinity maturation and the generation of plasma cells and memory B cells. The goal is to improve...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $218,900 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Alabama at Birmingham (UAB) to investigate the molecular determinants that influence flavivirus protease cleavage and how these factors affect viral fitness. The project aims to elucidate the proteolytic mechanisms used by flaviviruses, such as Dengue, Zika, West Nile, and Yellow Fever viruses, to...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) totaling $237,165 to the Research Foundation for the State University of New York (RFSUNY), doing business as SUNY Downstate Health Sciences University. The grant, effective from November 14, 2024 to October 31, 2026, will support research to elucidate the molecular mechanisms of viral internal ribosomal entry site (IRES)-mediated translation...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $254,250 to New York University (NYU) from July 1, 2025 to June 30, 2027. The funding supports research to understand how pathogenic alphaviruses, such as chikungunya virus, infect and spread through human microvascular endothelial cells. The research aims to identify viral and host factors that restrict alphavirus...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $806,693.00 to New York University (NYU) from June 12, 2025 to May 31, 2030. The grant supports research to elucidate the mechanisms governing lymphangiogenesis (growth of lymphatic vessels) in acute and homeostatic inflammation, and to determine the functional consequences of lymphatic encapsulation of B...
This Project Grant award, valued at $310,492.00 and awarded on November 14, 2024, is funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The award supports research to characterize the circumsporozoite protein (CSP)-specific memory B cell pool generated during Plasmodium infection or immunization, and to identify the impact of prior Plasmodium infection on the response to subsequent...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,170,041 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Hawaii (UH) to study the long-term safety and effectiveness of the Dengvaxia dengue vaccine in the Philippines. The key objectives are to determine the baseline dengue virus serostatus of Dengvaxia recipients, assess the long-term safety and effectiveness of the vaccine, and characterize the antibody and...