Project Grant R01AI192777
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of California, San Diego a $3.19 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 16, 2025, with a completion date of June 30, 2029. This grant funds investigator-initiated biomedical research examining the roles and regulation of tissue-resident CD8 T cells during persistent viral infection, utilizing the lymphocytic...
- Federal Project Grant Award Summary The University of California, San Diego received a $438,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 8, 2025, through June 30, 2027. The award supports basic immunological research focused on understanding the mechanisms that regulate immunoglobulin gene rearrangement, specifically investigating how enhancers and epigenetic...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded UC San Diego a $720,021 Project Grant effective February 6, 2026, through January 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports investigator-initiated biomedical research focused on developing broadly protective immunization strategies against Group A Streptococcus (Strep A), a significant global pathogen responsible for substantial...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $449,578 Project Grant to the University of California, San Diego under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period February 1, 2026 through January 31, 2031. This research initiative focuses on investigating the role of lytic polysaccharide monooxygenases (LPMOs), specifically chitin-binding protein D (CBPD), in the virulence and immunological...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $438,500 Project Grant to the University of California, San Diego under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 8, 2025, with a completion date of June 30, 2027. This award funds investigator-initiated biomedical research examining the sequence-specific determinants and impacts of NS2 (nonstructural protein 2) interactions with the Influenza A Virus...
- Federal Grant Award Summary The University of California, San Diego received a $438,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on July 21, 2025, with a completion date of June 30, 2027. This award supports the development of new tools to facilitate drug discovery targeting pathogen proteasomes, which represent an emerging therapeutic target for treating parasitic...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $381,608 Project Grant to the University of California, Los Angeles (UCLA) on February 18, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports research investigating the MAPK (Mitogen-Activated Protein Kinase) signaling cascade, specifically examining how multi-stability and molecular noise in dual-phosphorylation kinase cascades generate...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded University of California, Merced a Project Grant of $647,181 under the Allergy and Infectious Diseases Research program (CFDA 93.855) with an award date of February 1, 2026, and ultimate completion date of January 31, 2031. This award supports investigator-initiated biomedical research aimed at elucidating the regulatory mechanisms governing inflammasome assembly and activity....
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of California, San Diego a Project Grant totaling $439,250 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period February 4, 2026 through January 31, 2028. This research initiative focuses on discovering and characterizing mammalian serpins (serine protease inhibitors) as host-encoded viral protease inhibitors. The project involves...
- Federal Grant Award Summary The University of California, San Diego received a $3.02 million Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) awarded July 8, 2025, with a completion date of June 30, 2029. This grant funds basic immunological research investigating the Treg-IL-27 axis in immune regulation, specifically examining how regulatory T (Treg) cells produce interleukin-27 (IL-27) to...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded UC San Diego a Project Grant totaling $722,451 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for research activities spanning from May 5, 2026, through April 30, 2031. This award supports investigator-initiated biomedical research to establish and expand knowledge addressing infectious diseases, allergic conditions, and immunologic disorders through basic science investigations and translational studies. The funded research focuses on establishing the role of CMPK2 (cytidine/uridine monophosphate kinase 2), a mitochondrial protein, in bioenergetic and metabolic adaptation during macrophage activation and inflammatory response. The project will utilize myeloid-specific CMPK2 knockout mice and primary cell models to investigate how CMPK2-dependent mitochondrial DNA synthesis sustains ATP production, metabolic flexibility, and the proinflammatory phenotype necessary for effective immune responses. Research deliverables include scientific findings regarding mitochondrial protein function in immune cell metabolism, which will advance understanding of how targeting metabolic pathways can address persistent infections, chronic inflammatory disorders, and autoimmune conditions. This research will be conducted at UC San Diego's La Jolla, California campus.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $722.5k | 5/4/26 |