Project Grant R01AI189680
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University $433,125 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 21, 2025, for an exploratory research project extending through July 31, 2027. This project grant supports investigation of natural killer (NK) cell-mediated antibody-dependent cellular cytotoxicity (ADCC) enhancement through a novel oral adjuvant combined with the...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University a $605,778 Project Grant effective July 7, 2025, through June 30, 2030, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports fundamental biomedical research investigating the role of ARIADNE RBR E3 ubiquitin protein ligase 2 (ARIH2) in influenza A virus (IAV) replication and pathogenesis within airway epithelial cells....
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University a $354,416 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 2, 2026, with a completion date of January 31, 2028. This research initiative investigates novel peroxisome functions in Histoplasma capsulatum pathogenesis, specifically examining how the fungal pathogen exploits macrophage organelles to facilitate...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University a Project Grant of $433,125 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct basic research on influenza A virus (IAV) pathogenesis and acute respiratory distress syndrome (ARDS) mechanisms. The two-year research initiative, awarded July 2, 2025, and extending through June 30, 2027, investigates how the viral PB1-F2 protein...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University a Project Grant of $537,861 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, through July 31, 2030. This grant supports the development and advancement of pairwise survival analysis statistical methods for studying infectious disease transmission within households and close-contact groups. The research extends existing...
- Federal Project Grant Award Summary The Ohio State University received a $787,498 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 19, 2026, with a completion date of January 31, 2031. The grant supports fundamental immunology research investigating how STING (Stimulator of Interferon Genes) signaling mechanisms enhance innate immune responses and facilitate phagocyte...
- Federal Grant Award Summary The Ohio State University received a $227,588 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2027. The award supports research into bioprotein-mediated degradation of HIV-1 Rev protein as a novel therapeutic approach. The project involves developing protein-based proteolysis targeting chimeras (BIOPROTACs) that...
- Federal Project Grant Award Summary The Ohio State University received a $222,098 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 3, 2025, with completion targeted for January 31, 2027. This grant supports research investigating the role of the septin cytoskeleton in plasma membrane (PM) repair mechanisms. The research addresses a significant gap in understanding how...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University $189,057 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period commencing August 1, 2025 and concluding July 31, 2027. This project grant supports research investigating the efficacy of pre-exposure prophylaxis (PrEP) antiretroviral drugs in blocking Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) transmission...
- Federal Grant Award Summary The Ohio State University received a $758,645 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 2, 2026, with completion targeted for January 31, 2031. This research initiative investigates the mechanisms by which the liver clears gut-derived lipopolysaccharide (LPS) from blood circulation to prevent endotoxemia and associated systemic...
Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $790,507 Project Grant to The Ohio State University, with an award date of February 9, 2026 and completion date of January 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This research initiative investigates the mechanisms of simian arterivirus (SAV) entry, immune evasion, and zoonotic potential to advance epidemic preparedness efforts. The project employs molecular, biochemical, structural, and functional approaches to define SAV-receptor interactions and identify SAV proteins that antagonize the human innate immune response, with the goal of establishing proof-of-concept therapeutic strategies and revealing immune vulnerabilities for future outbreak prevention and mitigation. The research is supported by a collaborative effort including the University of Wisconsin–Madison as a sub-grantee, awarded March 17, 2026. Dr. Goldberg's laboratory at Wisconsin will conduct molecular analyses of non-human primate samples and bioinformatics analyses using metagenomics approaches to process biological samples (blood serum and plasma) for viral community analysis. The sub-awardee will assist in selecting samples for downstream analyses, coordinate VirScan analysis of human serum samples, and provide project coordination, personnel mentoring, data analyses, and results dissemination support to advance the overall research objectives.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $790.5k | 2/9/26 |
GrantNumber | Description | Subgrantee | Prime Award | Dollars Obligated | Updated At |
|---|---|---|---|---|---|
GR143754S | University Of Wisconsin System | Project Grant R01AI189680 | $190.0k | 3/17/26 |