Project Grant R01AI189330
- This Project Grant award of $463,615.00 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 Allergy and Infectious Diseases Research) will fund a study titled "VIOLA: STUDY OF VIREMIA ON LONG-ACTING ANTIRETROVIRAL THERAPY WITH CABOTEGRAVIR AND RILPIVIRINE" at the University of California, San Francisco. The study aims to assess cabotegravir and rilpivirine concentrations and viral resistance mutations among people with HIV who experience virologic failure...
- This Project Grant award of $285,816 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) will support research to enhance understanding of ADP-ribosylation (ADPR) and its role in HIV-1 latency and reactivation. The awardee, The Regents of the University of California, San Francisco, will conduct biochemical, proteomic, and cellular assays to identify global proteomic changes to ADPR during HIV-1 latency and reactivation,...
- This Project Grant award of $856,202 was provided by the National Institute of Allergy and Infectious Diseases (NIAID), which oversees the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program. The award will fund a 5-year study led by researchers at the University of California, San Francisco (UCSF) to investigate the role of IL-10 and IFN signaling in controlling the HIV reservoir and achieving functional HIV cure. The project aims to determine if enhancing IL-10 and...
- The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), awarded a $694,883 Project Grant to the Regents of the University of California, San Francisco (UCSF). The grant, awarded on September 15, 2025, supports research to evaluate a point-of-care urine tenofovir (TFV) assay developed by UCSF researchers as a tool to triage HIV drug resistance testing in South Africa. The project aims to compare the...
- This $624,902 Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to investigate the impact of the HIV accessory protein Vpr on epigenetic remodeling and viral persistence in myeloid cells. The 5-year project, starting on Apr 23, 2025, will focus on characterizing how Vpr induces epigenetic changes to facilitate sustained HIV transcription and latency reactivation, as well as...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $1,414,502 to the University of North Carolina at Chapel Hill (UNC-CH) to conduct research on assessing the variability in antiretroviral (ARV) drug penetration within tissues as a potential factor contributing to the persistence of HIV during treatment. The research aims to leverage advanced imaging techniques,...
- The National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded a $687,416 Project Grant to the J. David Gladstone Institutes in San Francisco, California. The grant is for a research project titled "Targeted Small Molecule Recruitment to Suppress the HIV Transcriptionally Active Reservoir" and runs from May 15, 2025 to March 31, 2030. The key objectives of this research project are to develop therapeutically effective...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support the development of new Bayesian causal structural discovery and reinforcement learning methods to investigate the effects of combination antiretroviral therapy (cART) regimens on viral suppression and depression outcomes for people living with HIV. The $145,299 award to The Johns Hopkins University will leverage...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $240,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Northwestern University to conduct research on characterizing the HIV-1 viral reservoirs that persist even under antiretroviral therapy (ART). The 2-year project aims to identify the cellular sources and genetic diversity of the HIV-1 reservoirs, as well as study the sources and characteristics of the residual viremia...
- This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support a study to evaluate field-based delivery of long-acting injectable antiretroviral therapy (LAI) for persons with HIV who are out of care in North Carolina. The $684,765 award, made on September 23, 2025, will fund a 3-year study conducted by the University of North Carolina at Chapel Hill. The study aims to examine the determinants,...
This federal Project Grant award of $819,603 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to implement novel strategies for long-acting antiretroviral therapy (ART) among people with criminal legal involvement (CLI) living with HIV. The project, titled "INSIDE START: Implementation of Novel Strategies for Long-Acting ART - People with Criminal Legal Involvement (CLI)," will be conducted by the University of California, San Francisco (UCSF) from August 2025 through July 2030. The key objectives are to understand the dynamics of care continuity for people with CLI living with HIV, explore the role of contextual factors in enabling post-incarceration HIV care, and evaluate the use of long-acting injectable ART formulations to maintain viral suppression among this population, even those with adherence challenges.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $819.6k | 8/21/25 |