Project Grant R01AI187515
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Alabama at Birmingham $131,307 through the Allergy and Infectious Diseases Research program (CFDA 93.855) on October 21, 2026, with a completion date of April 22, 2028. This F31 fellowship grant funds research to characterize the structural basis and functional roles of pili (hair-like bacterial appendages) produced by Burkholderia cepacia complex (BCC), a highly...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Alabama at Birmingham $1.48 million on August 12, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct molecular research on siderophore secretion and drug efflux mechanisms in Mycobacterium tuberculosis. The research investigates how M. tuberculosis acquires iron through siderophore (mycobactin and carboxy-mycobactin) secretion...
- Federal Grant Award Summary The University of Alabama at Birmingham received a $148,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 1, 2025, with a completion date of July 31, 2027. This research project investigates the role of calcium ions (Ca2+) in the assembly of the exosporium of Bacillus anthracis, the bacterium responsible for anthrax. The research focuses on...
- Federal Grant Award Summary The University of Alabama at Birmingham received a $587,885 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 18, 2025, with completion targeted for August 31, 2030. This research grant supports investigator-initiated biomedical research aimed at defining the structure-function relationships that govern influenza virus non-structural protein 1...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded University of Alabama at Birmingham $490,611 on April 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a five-year research project examining the role of regulatory dendritic cells in neonatal immune responses to influenza infection. The project will be completed by March 31, 2031. The research will deliver scientific discoveries and intellectual...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Alabama at Birmingham $496,628 through the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 18, 2026, for a Project Grant titled "FCRL Regulation in B Cell Tolerance and Malignancy." The research initiative, which extends through January 31, 2031, focuses on elucidating the mechanistic roles of Fc receptor-like (FCRL) molecules in B cell...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the Board of Regents of the University of Nebraska, through its University of Nebraska Medical Center (UNMC) division in Omaha, Nebraska, a Project Grant totaling $586,920 under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award, issued June 15, 2026, with completion targeted for May 31, 2031, funds biomedical research investigating the role of pyruvate...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Tufts University School of Medicine a $450,630 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period from August 1, 2025, through July 31, 2027. The award funds spatiotemporal investigation of interactions between pneumolysin, pulmonary epithelium, and polymorphonuclear leucocytes (PMNs/neutrophils) that contribute to...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $417,845 to the University of Nebraska Medical Center under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 9, 2025, for a project period extending through June 30, 2027. The award supports research to identify novel immune determinants influencing Staphylococcus aureus biofilm infection using Collaborative Cross (CC) mouse lines. The research addresses gaps in...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $575,966 Project Grant to the University of California, Los Angeles on July 13, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research project, titled "How Surface Sensing and Second Messenger Signal Dynamics Control Time-Dependent Biofilm Outcomes," will extend through June 30, 2031, and focuses on understanding the molecular...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Alabama at Birmingham $512,842 on July 13, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate how capsule O-acetyltransferases modulate pneumococcal fitness. The award funds a five-year research project (completion date: June 30, 2031) examining the function of O-acetyltransferase (OACT) enzymes and their contribution to bacterial fitness in Streptococcus pneumoniae. Specifically, the research addresses mechanisms by which these enzymes mediate O-acetylation of bacterial capsule polysaccharides, the factors driving conservation of this modification among pathogenic pneumococcal serotypes, and how OACT enzymes coordinate with capsule synthesis machinery to modulate pneumococcal virulence and survival in natural niches. This basic research project aims to generate scientific knowledge on pneumococcal capsule biochemistry with potential applications to vaccine development and therapeutic targeting, given the critical role of pneumococcal infections in ongoing public health challenges. The investigation leverages UAB's established expertise in pneumococcal biology and capsule structure characterization, positioning the institution to deliver research findings relevant to understanding bacterial pathogenesis mechanisms and informing future intervention strategies against pneumococcal disease.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $512.8k | 7/13/26 |