This federal Project Grant award, funded by the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), supports a comprehensive study to examine the relationship between sleep disturbances and cognitive decline, including the risk of Alzheimer's disease and related dementias (ADRD), across the adult lifespan.
The University of California, San Francisco (UCSF) is the prime awardee, receiving $729,553 to lead this 5-year research project. UCSF will leverage data from six longitudinal cohorts, two with substantial Black and Mexican American participation, to create a diverse sample of approximately 35,000 adults aged 30-104 with objective and subjective sleep measures, as well as regular cognitive assessments spanning up to 60 years. The University of Pittsburgh will participate as a sub-awardee, with Dr. Wallace providing scientific and statistical support for the project. The research aims to elucidate the bi-directional relationship between sleep disturbances and cognitive aging, and identify underlying mechanistic pathways at different life stages, in order to inform early detection and intervention strategies for ADRD.
Generated 3/25/25, 2:57 AM