The Federal Project Grant award R01AG083735, totaling $835,868.00, was granted by the National Institute on Aging (CFDA 93.866 - Aging Research) to the Trustees of Boston University Medical Campus. The grant aims to develop a digital cognitive health resource that leverages the Boston University Alzheimer's Disease Research Center (BU ADRC) cohort data.
The key products and services to be delivered under this grant include:
- Collecting and characterizing digital cognitive metrics (DCOG) from the BU ADRC cohort, comparing those at high risk (A/T/N positive) versus low risk (A/T/N negative) for Alzheimer's disease (AD).
- Assessing the relationship between DCOG phenotypes, vascular risk factors, and neuroanatomic measures.
- Building machine learning models using DCOG phenotypes, vascular risk factors, and biomarkers to predict cognitive health and enable better diagnosis, treatment, and prevention of AD.
Additionally, the University of Massachusetts Medical School will serve as a sub-awardee, providing statistical and machine learning analysis expertise to identify potential digital biomarkers for cognitive health from the BU ADRC data.
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