Project Grant R01AA033377
- The National Institute on Alcohol Abuse and Alcoholism awarded Children's Research Institute $648,180 on June 20, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate mechanisms and potential pharmacotherapy of neurocognitive deficits in fetal alcohol spectrum disorders. The research examines the long-term neurobehavioral impact of prenatal alcohol exposure, with focus on apolipoprotein E (APOE) signaling in the motor cortex as a therapeutic target. The project builds on...
- The National Institute on Alcohol Abuse and Alcoholism awarded the Seattle Institute for Biomedical and Clinical Research $474,762 on May 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate how blast-induced traumatic brain injury and chronic alcohol use interact to accelerate neurodegeneration and Alzheimer's disease and related dementia in preclinical rodent models. The research examines the glymphatic system—the brain's waste clearance mechanism—as a potential...
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of Maryland, Baltimore $1.737 million on September 26, 2025, under the Alcohol Research Programs (CFDA 93.273) to investigate sensory cortical deficits in fetal alcohol spectrum disorders using a ferret model. The research combines in vivo electrophysiology and optical imaging of intrinsic signals to test whether developmental alcohol exposure causes synesthetic responses, disrupts tonotopic organization in auditory...
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of North Carolina at Chapel Hill $1,170,144 on September 20, 2025, under the Alcohol Research Programs CFDA 93.273, to conduct a prospective study of fetal alcohol spectrum disorder (FASD) risk assessment integrating maternal alcohol exposure, maternal mental health, and paternal risk factors. The award funds a research phase (R33) that builds on completed preliminary work (R61) to develop and validate a multivariate...
- The National Institute on Alcohol Abuse and Alcoholism awarded San Diego State University Foundation $435,083 on July 15, 2026, under the Alcohol Research Programs (CFDA 93.273) to develop and validate BRAIN-ONLINE EN ESPAÑOL, a web-based screening tool for fetal alcohol spectrum disorders (FASD). The project addresses diagnostic barriers in FASD detection by testing the Spanish-language version of BRAIN-ONLINE in youth at risk for FASD and typically developing comparison children....
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of Florida $283,376 on May 15, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct a Phase 1 clinical trial assessing sensory-enriched occupational therapy intervention in children with fetal alcohol spectrum disorders (FASD). The award funds a two-phase R61/R33 study examining whether sensory-enriched occupational therapy improves neurological sensory processing deficits in 6- to 8-year-old children...
- The National Institute on Alcohol Abuse and Alcoholism awarded New York University $746,805 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate developmental pathways linking prenatal alcohol exposure to adult externalizing outcomes in adolescents. The research, titled the DREAMS study (Developmental Research on Externalizing Outcomes Among Youth with Prenatal Alcohol Exposure: Mediating Role of Cognitive Control and Sleep), leverages the NIH SAFE PASSAGE and...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Ohio State University $474,223 on May 11, 2026, under the Alcohol Research Programs (CFDA 93.273) to elucidate brain region- and cell-specific mechanisms of alcohol-induced developmental neurotoxicity and develop precision interventions targeting neuroprotection. The research addresses fetal alcohol spectrum disorder (FASD), which contributes significantly to intellectual disabilities with a prevalence rate of 1-5% in the...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of New Mexico Health Sciences Center $160,744 on March 9, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate electrophysiological mechanisms of prenatal alcohol exposure (PAE) effects on cognitive control. The project combines translational touchscreen testing and in vivo electrophysiology to determine how PAE impairs executive function domains in mouse models. The research hypothesizes that...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Medical College of Wisconsin, Inc., $248,959 on September 12, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a five-year longitudinal study examining reciprocal associations between brain function and alcohol use trajectories in adolescents and young adults. The recipient will assess prospective long-term associations between reward processing, cognitive control, and alcohol use patterns using two large...
The National Institute on Alcohol Abuse and Alcoholism awarded the University of Washington $725,022 on August 20, 2026, under the Alcohol Research Programs (CFDA 93.273) to conduct longitudinal and cross-sectional research examining age-related brain changes in adults with fetal alcohol spectrum disorders. The project will follow 60 adults with FASD and 30 healthy comparison adults aged 30–65 years at baseline through a series of neuroimaging and cognitive assessments to characterize brain maturation trajectories as individuals with prenatal alcohol exposure age. The study addresses a documented gap: while prior research has established that prenatal alcohol exposure produces detectable changes in brain volume, structure, and functional connectivity in children and adolescents—including smaller total brain volume, abnormalities in the corpus callosum, and atypical developmental patterns suggesting both disrupted maturation and accelerated aging—no longitudinal studies currently examine these brain outcomes in middle-aged and older adults with FASD. The research is designed to determine whether brain impacts observed in younger cohorts extend into midlife and beyond. Performance occurs in Seattle, Washington, with a period of performance through May 31, 2031. The University of Washington Office of Sponsored Programs administers the award as the recipient institution.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $725.0k | 8/24/26 |