Project Grant P50NS132955

Award Date 8/15/24
Completion Date 7/31/28
Dollars Obligated $1.5M
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Florida, USA
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This $1,472,597 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports cutting-edge research on myotonic dystrophy types 1 and 2 (DM1 and DM2) at the University of Florida and the University of Rochester. The key products and services to be delivered include:

  • Developing and characterizing new mouse models for DM2 to accelerate preclinical research and therapy development
  • Clarifying molecular mechanisms underlying therapeutic approaches for DM1 using a new knockin mouse model
  • Conducting remote patient assessments and establishing a DNA bank to study disease severity, repeat length, and genetic factors in DM1 and DM2
  • Expanding shared research resources and providing training for the next generation of DM researchers

The University of Rochester is a sub-awardee supporting various aspects of the clinical research, patient registry, and training program components. The award period runs from August 2024 to July 2028.

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