Project Grant P01AI202602
- The National Institute of Allergy and Infectious Diseases awarded the Regents of the University of Michigan $598,906 on April 10, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate mechanisms of respiratory viral infections in hospitalized children. The research examines how early-life respiratory tract infections contribute to asthma development by analyzing nasal transcriptomes in children hospitalized with bronchiolitis or asthma. The project team...
- The National Institute of Allergy and Infectious Diseases awarded the University of Missouri System $3,987,706 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate immune mechanisms shaping airborne influenza transmission through an integrated program combining swine and human studies with multiscale computational modeling. The research addresses the mechanistic gap in understanding how host immunity and environmental conditions govern...
- The National Institute of Allergy and Infectious Diseases awarded the Regents of the University of Michigan $411,078 on April 7, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to model perinatal exposure to diverse pathogenic microbes and assess the functional programming of innate lymphoid cells, specifically group 1 innate lymphocytes and natural killer cells. The research addresses how early-life microbial exposure shapes immune system development and innate...
- The National Institute of Allergy and Infectious Diseases awarded the Regents of the University of Michigan $329,539 on July 24, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support the Transdisciplinary Training in RNA and Infection (TRAIN) program. TRAIN integrates 32 preceptors from 14 departments across 5 schools and institutes at the University of Michigan to mentor six graduate students in RNA biology, infectious disease research, and drug...
- The National Institute of Allergy and Infectious Diseases awarded the Regents of the University of Michigan $2.284 million on August 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on microbial interactions combating antibiotic-resistant bacteria (MI-CARB). The research employs a systems biology approach to understand pathogenesis of nosocomial infections caused by three pathogen groups: vancomycin-resistant enterococci (VRE),...
- The National Institute of Allergy and Infectious Diseases awarded the Regents of the University of Michigan $677,822 on June 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to estimate and understand population susceptibility to coccidioidomycosis, an emerging fungal infectious disease in the U.S. Southwest. The project advances methods for estimating immunity to Coccidioides in the general population using cell-mediated immunity tests and population-level...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the Regents of the University of Michigan $419,274 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 8, 2025, with a completion date of June 30, 2027. This Project Grant funds research to understand the influence of climate and environmental factors on blastomycosis incidence and seasonality in the Northern Great Lakes states. The research compiles and analyzes the...
- The National Institute of Allergy and Infectious Diseases awarded the University of Missouri System $805,253 on July 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate mechanisms underlying airborne transmission of seasonal influenza A viruses, specifically H1N1 and H3N2 subtypes. The recipient will characterize aerosol particle size distributions and virion morphologies of H1N1 and H3N2 using samples from human patients, laboratory-generated...
- The National Institute of Allergy and Infectious Diseases awarded the Regents of the University of Michigan $186,758 on February 9, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on infection-induced cell cycle diversion and macrophage inflammatory biogenesis. The award funds investigation into how bacterial infection of macrophages, specifically by methicillin-resistant Staphylococcus aureus (MRSA), triggers structural and biochemical...
- The National Institute of Allergy and Infectious Diseases, part of the Department of Health and Human Services, awarded the Regents of the University of Michigan $194,400 on April 1, 2026 under the Allergy and Infectious Diseases Research program (CFDA 93.855). The project examines the role of organelle membrane contact sites in macrophage antifungal immune responses, with particular focus on Candida albicans infection. Preliminary data indicate that the endoplasmic reticulum stress sensor IRE1A...
The National Institute of Allergy and Infectious Diseases awarded the Regents of the University of Michigan $2.959 million on August 25, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support the Michigan Influenza Transmission Research Center's observational studies of human influenza transmission. The award funds three coordinated research projects examining influenza transmission through the epidemiologic triangle framework of pathogen, host, and environment. Project 1 investigates how virus dynamics and coinfections with other respiratory pathogens relate to transmission risk. Project 2 examines host immunity by leveraging a 15-year household study specimen collection to define how the specificity of humoral and cellular immune responses to influenza glycoproteins influences infectiousness and susceptibility to infection. Project 3 models the impacts of environmental factors on transmission using data from three different household studies. The research builds on continuously funded cohorts of observational studies of influenza and other respiratory virus transmission dating to 2010, incorporating robust analysis and inference methods to dissect transmission events from real-world data. Work is performed at the University of Michigan, Ann Arbor, Michigan. The performance period runs through June 30, 2031. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $3.0m | 8/25/26 |