Cooperative Agreement NU58DP006101

This Project Grant award from the National Cancer Institute (NCI), under the Cancer Treatment Research program (CFDA 93.395), will support research to develop a targeted colorectal cancer (CRC) screening strategy for adults aged 45-49. The $224,099 grant, awarded on January 1, 2025, will enable the University of California, San Diego (UCSD) to conduct a pilot trial to assess the acceptability of CRC screening in this age group and identify effective strategies for screening implementation. It...

This Project Grant award from the National Cancer Institute (NCI), under the Cancer Detection and Diagnosis Research program (CFDA 93.394), will support the development and clinical validation of an Optical Coherence Tomography (OCT) system and two specialized OCT imaging probes to enhance colorectal cancer screening. The $1,471,777 award to The General Hospital Corporation (doing business as Massachusetts General Hospital) aims to create an OCT system that can obtain 3D microscopic images of...

This federal Project Grant award from the National Cancer Institute (CFDA 93.398 Cancer Research Manpower program) provides $197,640 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to develop implementation strategies to initiate colorectal cancer (CRC) screening in previously unscreened individuals aged 45 to 54 at a predominantly Black community health center in Boston, Massachusetts. The key objectives are to: (1) identify system-level determinants of...

This Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) provides $696,852 to Harvard T.H. Chan School of Public Health to optimize a mobile messaging intervention to increase colorectal cancer (CRC) screening rates among patients at community health centers (CHCs). The project aims to use a two-phase process to first focus on maximizing patient engagement with a text message-based CRC screening campaign, and then use a factorial design...

This federal Project Grant award of $622,913 from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research (CFDA 93.393) program will fund a 5-year study to evaluate a multilevel intervention to increase colonoscopic follow-up after abnormal stool-based colorectal cancer screening in a community safety-net setting. The study will be conducted by the University of California, Los Angeles (UCLA) in partnership with the Northeast Valley Health Corporation (NEVHC), a...

This federal Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) provides $670,534 to Northwestern University to develop an optical hyperspectral nanoscale chromatin analysis technology for colorectal cancer risk-stratification. The goal is to create a highly accurate, low-cost screening test that can be administered in primary care settings to identify patients who should undergo colonoscopy, with a target of 99.5% negative predictive...

This Project Grant award from the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research) provides $637,596.00 to develop and test an intervention to reduce cancer information avoidance and increase colorectal cancer screening. The intervention is a video-based strategy designed to increase self-efficacy and positive affect, thereby reducing defensive avoidance of colorectal cancer information. The project involves a randomized controlled trial (RCT) to evaluate the...

This Project Grant award of $1,403,822 from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research (CFDA 93.393) program supports a multi-center, prospective trial to examine the performance of the Fecal Immunochemical Test (FIT) in Lynch Syndrome (LS) patients undergoing colorectal cancer (CRC) surveillance. The study aims to measure FIT test characteristics, evaluate personalized surveillance strategies integrating non-invasive tests with colonoscopy, and...

This Project Grant award of $1,475,079 from the Health Resources and Services Administration (HRSA) under the Health Center Program (CFDA 93.224) aims to accelerate colorectal cancer (CRC) screening and referral for care and treatment in underserved areas of Philadelphia. The prime awardee, Resources For Human Development, Inc. (RHD), will collaborate with the Abramson Cancer Center, Spectrum Health Services, and the Health Federation of Philadelphia to increase CRC screening rates by over 1,000...

This Project Grant award, valued at $625,452.00 and effective January 1, 2025, was provided by the National Institute on Aging (CFDA 93.866 - Aging Research) to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. The funding supports a research project to develop and evaluate a clinical decision support intervention to guide colorectal cancer screening decisions in older adults, with a focus on incorporating life expectancy considerations. The project will involve...