Project Grant N001782510032

This Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) provides $400,000 to the Massachusetts Institute of Technology (MIT) to develop the ENZYME research ecosystem. The goal is to enable the automatic generation of derivatives for arbitrary programs written in LLVM-based languages, making it easier for scientists and engineers to apply modern algorithms like machine learning to their domains without...

This Project Grant award of $600,000 from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) supports research to optimize the performance of transformer-based artificial intelligence (AI) models on mobile devices. The project aims to develop new techniques related to memory hierarchy management, including performance modeling, formal transformation approaches, and memory allocation strategies. This will enable more efficient...

This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research on improving transformation and regeneration methods for maize and other recalcitrant plant species. The $524,852 award to Virginia Polytechnic Institute & State University aims to provide a thorough understanding of the molecular events leading to successful plant formation from differentiated tissues. The goal is to develop new strategies for enhancing...

This Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) aims to develop a revolutionary DNA sequencing platform that surpasses existing technologies in accuracy and cost. The $384,418 award to Xgenomes Corp. will fund the development of a super-resolution single-molecule sequencing method that can read short sequence "words" rather than single nucleotides, enabling highly accurate and cost-effective genomic analysis. The...

The University of Missouri System received a $598,103 Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) to develop cutting-edge artificial intelligence (AI) methods based on transformers to more accurately infer gene regulatory relationships (gene regulatory networks) from large volumes of omics data. The project aims to achieve three specific objectives: (1) predicting transcription factor binding sites...

Geometric Data Analytics Inc. was awarded a $199,898 Project Grant from the Department of Energy Office of Science on February 14, 2022 to develop distributed topological fingerprints for automating anomaly search and testing (DTFAAST). The grant was awarded under the Office of Science Financial Assistance Program (CFDA #81.049), which supports basic research to deliver scientific discoveries and tools that transform understanding of nature and advance U.S. energy security and economic...

The National Center for Advancing Translational Sciences (NCATS), under CFDA Program 93.350, has awarded a $331,034 Project Grant to Vector Surgical LLC to develop the Gene Therapy Catheter (GTC) - an electrical pulsing device designed to enhance the delivery of adeno-associated virus (AAV) gene therapy to the liver. The GTC aims to improve the efficiency and safety of liver-directed gene therapies by combining local delivery with electrical pulsing and a double-balloon system to isolate the...

The National Human Genome Research Institute (NHGRI) awarded a $122,981 Project Grant under the Human Genome Research program (CFDA 93.172) to Tennessee State University (TSU) to establish the AGTC (Attaining Genomics Talent Cloud) program. This 5-year initiative aims to increase diversity and inclusion in the genomics workforce by providing intensive research training and mentorship to undergraduate students, particularly from underrepresented minority and disadvantaged backgrounds, at TSU (a...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program provides $540,524 in funding to the University of Massachusetts Medical School (UMass Medical) from March 1, 2025 to February 28, 2029. The award supports the development and optimization of an enhanced synthetic RNA "on" switch based on the T3H38 ribozyme. This...

This Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) provides $452,375 to The Trustees of Columbia University in the City of New York to develop a platform for rapid and efficient generation of multi-site sequence variants using template-guided gene synthesis. The project aims to advance this synthesis approach by optimizing predictive algorithms, experimental protocols, and robotic automation to produce kilobase-sized DNA constructs up...