The National Institute of Child Health and Human Development (NICHD), through its Child Health and Human Development Extramural Research program (CFDA 93.865), awarded a $135,864 Project Grant to the Whitehead Institute for Biomedical Research to conduct research on nervous system regeneration. The project aims to develop a miniature transparent fish, Danionella cerebrum, as a new model system for studying mechanisms that promote nervous system regeneration. Key objectives include generating a single-cell transcriptome atlas of the Danionella brain across homeostatic and regenerative states, and using genetic tools and functional imaging to characterize neural dynamics during regeneration. The research seeks to accelerate understanding of fundamental aspects of neural regeneration, with potential to inform therapeutic approaches for nervous system injury and degeneration. Whitehead Institute, a non-profit biomedical research institute, has extensive experience in federally funded projects across various biomedical domains.
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