This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, will support research to investigate the effects of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) on placental function and children's growth and development. The total funding amount is $695,853 and the award period is from December 1, 2024 to November 30, 2029.
The research will leverage three existing cohorts to...
This $533,723 federal Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) will support research at Wayne State University to investigate how exposure to per- and polyfluoroalkyl substances (PFAS) impacts placental inflammation and susceptibility to preterm birth. The researchers will examine how PFAS exposure alters interferon signaling and glycoprotein distribution in the placenta, and whether this increases...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program aims to investigate the neurotoxic and neurodevelopmental health risks of per- and polyfluoroalkyl substances (PFAS). The $546,350 award, which begins on January 13, 2025 and runs through October 31, 2029, will fund research to: (1) define the chemical interactions that mediate neuronal uptake and accumulation of PFAS, (2) elucidate the neurotoxic...
This federal Project Grant award, funded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports research to investigate the ovarian disrupting effects of per- and polyfluoroalkyl substances (PFAS) on female reproductive health and fertility. The $561,584 grant awarded to Rutgers, The State University of New Jersey, will integrate in vivo, in vitro, and in silico models to study how exposure to PFNA, a widely used...
This $229,100 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research to investigate the occurrence and health effects of per- and polyfluoroalkyl substances (PFAS) exposure among U.S. volunteer firefighters.
The study aims to (1) assess the prevalence, predictors, and exposure sources of PFAS in this population, and (2) examine associations between PFAS levels and dyslipidemia (imbalanced...
The National Institute of Environmental Health Sciences (NIEHS) awarded a $499,454.23 Project Grant under the Environmental Health (CFDA 93.113) federal grant program to the University of Massachusetts (UMass) to develop edible sorbent therapies that can mitigate dietary exposures to per- and polyfluoroalkyl substances (PFAS), also known as "forever chemicals". The project aims to create multicomponent sorbents derived from naturally occurring or generally recognized as safe...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $1,968,864 to Purdue University to conduct research evaluating and comparing the neurotoxic effects of exposure to various per- and polyfluoroalkyl substances (PFAS), including legacy PFOA and replacement chemicals PFBA and GenX. The research aims to characterize the impact of low-dose developmental PFAS exposure on...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $488,349 to the University of Southern California (USC) to conduct research examining the association between exposure to per- and polyfluoroalkyl substances (PFAS) and the risk of diabetic kidney disease (DKD) in youth with type 2 diabetes (T2D). The project aims to prospectively investigate the link between PFAS exposure and...
This $478,503 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) supports research to investigate the impact of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) on the development of non-alcoholic fatty liver disease (NAFLD) in children.
The award will leverage the existing GUSTO mother-child cohort in Singapore to conduct comprehensive assessments, including proton magnetic resonance...
This $701,121 federal Project Grant award from the Department of Defense's Defense Health Agency, issued under the Military Medical Research and Development program (CFDA 12.420), supports research on the ovarian-disrupting effects and mechanisms of per- and polyfluoroalkyl substances (PFAS). The project is being conducted by Rutgers, The State University of New Jersey's RBHS-School of Nursing over a 3-year period from September 2023 to September 2026. The research aims to develop a better...
This federal Project Grant award, funded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports a two-phase research project conducted by Boston University Medical Campus. The total award amount is $121,057, with a project period from December 15, 2024 to November 30, 2026.
The research aims to investigate the associations between per- and polyfluoroalkyl substance (PFAS) mixtures and adverse pregnancy outcomes, such as spontaneous abortion, preterm birth, and small for gestational age births, among Black women. The K99 phase will evaluate the PFAS mixture-pregnancy outcome relationships and examine perceived stress as a modifying factor. Building on these findings, the R00 phase will use metabolomics data to identify biological pathways related to PFAS toxicity and quantify the mediating role of these pathways on the PFAS mixture-pregnancy outcome associations, again considering the modifying effect of perceived stress. This research is expected to address critical knowledge gaps in understanding the perinatal toxicity of PFAS mixtures in an underserved population, informing public health interventions to reduce health disparities.