Project Grant K99AI187733
Award Date 8/21/25
Completion Date 7/31/27
Dollars Obligated $123K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
Similar Awards
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $831,755 over 5 years to New York University (NYU) to conduct research on the role of lung-resident macrophage subsets in regulating type 2 immune responses and trained immunity. The research aims to elucidate the distinct functions of different macrophage populations, particularly nerve- and...
- This $152,250 Project Grant awarded on July 16, 2025 by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855), supports research by Drexel University to investigate the use of nanoparticles to manipulate macrophage metabolism and phenotype. The goal is to trigger a reparative, pro-healing response in macrophages by delivering apoptotic cell-mimetic metabolite payloads encapsulated in...
- This Project Grant award for $160,954.00, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to define the mechanisms of macrophage-specific killing of the intracellular bacterial pathogen Shigella flexneri. The research aims to better understand how macrophages, a key immune cell, restrict and eliminate this leading cause of diarrheal disease and dysentery worldwide. The work...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $441,375 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Children's Hospital Medical Center (UEI JZD1HLM2ZU83) to conduct research on the "Transcriptional Mechanisms of Chronic Inflammation in Genetically Diverse Tissue Macrophages." The project will focus on understanding the genetic factors and regulatory mechanisms that contribute to the development of metabolic...
- The University of California, Davis received a $126,738 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) on May 29, 2025. The grant supports research to investigate extramedullary granulopoiesis and immune responses in human skin using a novel skin-on-a-chip model. The project aims to provide mechanistic insight into the migration of hematopoietic stem and progenitor cells into human skin and their role in...
- The Project Grant award of $189,376 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855) supports research to unravel the interactions between skin microbiota and the immune system that drive early-life commensal tolerance. The research aims to better understand the mechanisms by which conserved microbial signals, specifically those recognized by Toll-like Receptor 2 (TLR2), promote the...
- This Project Grant award of $104,262, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to explore the relationship between genetic variants, transcriptional responses, and tuberculosis (TB) infection outcomes in macrophages derived from genetically diverse mice. The project aims to understand the basis for variability in TB infection outcomes, which may help identify ways to...
- This $243,713 Project Grant awarded on January 27, 2025 by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) program supports research to characterize mechanisms by which HIV-infected macrophages evade antibody-dependent cell-mediated cytotoxicity (ADCC) by natural killer (NK) cells. The objective is to determine how infected macrophages, which serve as a physiologically relevant viral reservoir, resist NK cell...
- This Project Grant award, valued at $127,527.00 and running from November 1, 2025 to April 30, 2028, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The funding supports research by Duke University to investigate the role of the RGS12 gene locus in regulating macrophage function, particularly in the context of granuloma formation during mycobacterial infections like...
- This $174,767 Project Grant from the National Institutes of Health's National Institute of Allergy and Infectious Diseases will fund research into host defense mechanisms of resident peritoneal macrophages. Specifically, the awardee, Washington University, will examine how large peritoneal macrophages interact with mesothelial surfaces and promote clotting in the peritoneal cavity. This appears aimed at better understanding the immune response against infections and tumors in the peritoneum. The...