Project Grant K99AA031509

Award Date 5/15/25
Completion Date 4/30/27
Dollars Obligated $156K
Federal Grant Program
93.273
Assistance Type
Project Grant
Place of Performance
Worcester, MA 01655, USA
Similar Awards
This $498,121.57 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), will support research to investigate the neural mechanisms that drive maladaptive coping strategies and subsequent alcohol use following exposure to stress. The principal investigator will utilize an animal model to study how dysfunction in the corticolimbic circuitry, specifically the prelimbic cortex and basolateral amygdala, contributes...
This federal Project Grant award, with ID R01AA031832, was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program. The $499,442 award will fund research to investigate the role of brain-derived neurotrophic factor (BDNF) signaling in the ventral hippocampus (VHP) and its contribution to the acute anxiolytic and social effects of alcohol, as well as the promotion of alcohol preference over social...
The federal Project Grant award R15AA031562, totaling $431,918.00, was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) to Bryant University. The grant supports research to investigate the neural circuitry mechanisms underlying maladaptive reward memories related to alcohol addiction in Drosophila (fruit flies). The project aims to leverage the genetic tractability of Drosophila and advanced neurogenetic tools to...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) grant program, supports research on the role of beta2 nicotinic acetylcholine receptors in the insula-BNST pathway in relation to ethanol consumption and abstinence-induced negative affect. The total funding amount is $103,948.00 and the award date is January 31, 2025, with an ultimate completion date of August 31, 2027. The awardee is Wake...
This $143,784 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program, supports research to investigate the effects of adolescent opioid exposure on alcohol-induced pain sensitivity (hyperalgesia) in adult mice. The primary objectives are to test the hypothesis that early-life opioid exposure will increase the magnitude of alcohol-induced pain sensitivity in adulthood, and that this effect...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program, supports research to investigate the role of a novel dynorphinergic extended amygdala circuit in pain- and fentanyl abstinence-facilitated alcohol drinking. The $159,056 award, granted on January 12, 2025, with a completion date of June 30, 2026, will enable researchers at The Washington University in St. Louis to use...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $581,869 Project Grant under the Alcohol Research Programs (CFDA 93.273) to The University of Kentucky Research Foundation. The grant will fund a rigorous 4-year crossover study to translate preclinical findings on the role of glucocorticoid receptors in alcohol use disorder (AUD) to humans. The study will use the selective glucocorticoid receptor antagonist PT150 to examine its effects on stress-induced and alcohol-induced...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $275,171.12 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of California, Los Angeles (UCLA) on July 24, 2024. The grant will support a clinical neuroscience study to understand stress coping mechanisms in individuals with Alcohol Use Disorder (AUD) compared to matched controls. The research aims to objectively assess chronic stress and examine dynamic functional connectivity within the...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) will fund research to characterize the effects of adolescent binge alcohol consumption on behavioral profiles, somatostatin neuron function, and functional connectivity in the prefrontal cortex, with a focus on sex differences. The $597,000 award to The Pennsylvania State University will leverage a multidisciplinary approach spanning slice...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $545,282 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Colorado-Denver to study neural mechanisms associated with emotion regulation and alcohol cue reactivity during early abstinence from alcohol use disorder (AUD). The 5-year project aims to determine how neural function related to cognitive reappraisal and alcohol cue processing changes across early AUD treatment, and whether...

This federal Project Grant award, provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), supports research on the role of BNST PKCδ neurons in compulsive ethanol intake behaviors. The $156,204 award, with a period of performance from May 15, 2025 to April 30, 2027, will fund a study using in vivo fiber photometry and ex vivo slice wide-field calcium imaging to evaluate adaptations in BNST PKCδ neuron activity across ethanol abstinence periods and in response to ethanol exposure. The research aims to provide novel insights into the neural circuit mechanisms underlying compulsive alcohol use disorder behaviors, with the goal of informing the development of targeted therapeutic interventions. The award is being provided to the University of Massachusetts Medical School, a prominent research institution with a robust track record of securing federal grants and contracts across various biomedical research domains.

Generated 6/17/25, 2:19 AM