This federal Project Grant award, funded by the National Institute on Aging under CFDA program 93.866 Aging Research, aims to develop and pilot a patient decision aid to support shared decision-making between clinicians, patients, and caregivers regarding pharmacologic therapies for dementia. The $234,000 grant will be awarded to the University of Colorado-Denver and has a project period from September 2024 to August 2026. The key products and services to be delivered through this grant include:...
This Cooperative Agreement award, totaling $1,419,954.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) grant program. The award aims to advance adaptive deep brain stimulation (aDBS) therapy for Parkinson's disease through the following key objectives: Reduce the complexity and risk of chronic cortical sensing by placing leads in the subgaleal space rather...
This $834,094 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to advance research on post-stroke cognitive impairment and dementia (PSCID). The funding will support a multi-year effort leveraging a national stroke registry and Medicare data to determine the incidence and prevalence of PSCID, identify associated risk factors, and explore potential pharmacological prevention strategies. Key aspects of the research include a patient-centered approach,...
This $2,307,536 federal Project Grant, awarded by the National Institute on Aging (CFDA 93.866 - Aging Research), will leverage a natural experiment to examine the effects of integrated palliative care on health service outcomes and disparities in Parkinson's disease and Lewy body dementia. The primary awardee, The Trustees of the University of Pennsylvania, will: Examine patterns of palliative domain care and disparities across U.S. Parkinson's specialty centers; and Test the effects of a...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $469,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Michigan Technological University. The grant, titled "Dissecting Neural Circuit Mechanisms Underlying Pallidal Deep Brain Stimulation," will fund research to identify the neural elements and circuits necessary for the therapeutic effects of deep brain stimulation (DBS) of the globus...
The National Institute on Aging (NIA) awarded a $1,010,368 Project Grant under the Aging Research federal grant program (CFDA 93.866) to Koronis Biomedical Technologies Corp. (KBT) to develop and validate an interactive gaming platform to facilitate cognitive interventions for individuals living with mild cognitive impairment (MCI) or Alzheimer's disease and related dementias (AD/ADRD). The goal is to create an in-home cognition training system that provides evidence-based cognitive activities...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will fund a $811,443 cluster randomized trial to evaluate the impact of a shared decision-making (SDM) training program for breast surgeons and a patient decision aid for women aged 70+ with early-stage, low-risk breast cancer. The goal is to reduce the use of low-value treatments, such as mastectomy, sentinel lymph node biopsy, and radiation therapy after breast-conserving surgery, without...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $749,108 to the University of California, Irvine to conduct research on how memory failures lead to decision-making failures in older adults. The project aims to understand the influence of different types of memory (item, context, statistical learning) on decision-making, using computational frameworks, neuroimaging, and advanced diffusion imaging. It will assess how memory specificity...
This federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) provides $655,638 to the University of Denver to develop and test synthetic protein mimetics as potential therapeutics for Lewy body dementia (LBD). The key products and services being delivered under this 2.5-year award include: Optimization and testing of the pharmaceutical properties of oligopyridylamide (OP) synthetic protein mimetics to inhibit alpha-synuclein aggregation and Lewy...
This $500,000 Project Grant was awarded on September 15, 2024 by the National Institute on Aging (CFDA 93.866 Aging Research program) to Neucyte Inc., a minority-owned small business specializing in advanced biomedical research and development. The funding will support the development of a miniaturized "mini-brain" microphysiological system (MPS) platform using Alzheimer's disease (AD) patient-derived cells. The goal is to create a scalable, reproducible in vitro brain model that can...