Project Grant K38HL175026
Award Date
9/1/24
Completion Date
8/31/26
Dollars Obligated
$105K
Federal Agency
National Heart Lung and Blood Institute
Awardee
Duke University (TP7EK8DZV6N5)
Federal Grant Program
93.837
Assistance Type
Project Grant
Place of Performance
Durham, NC 27710, USA
Similar Awards
This federal Project Grant award, totaling $753,813 and provided by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), supports research to develop novel machine learning techniques for predicting cardiovascular outcomes in patients with clonal hematopoiesis of indeterminate potential (CHIP). The key goals are to use cardiac MRI imaging and genomic data to: 1) Develop a machine learning model to accurately identify CHIP patients and predict their risk...
The National Heart, Lung, and Blood Institute (NHLBI) has awarded a $165,080 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the Dana-Farber Cancer Institute (DFCI) in Boston, MA. The grant will fund a 5-year research project led by Dr. Lachelle D. Weeks to define the relationship between clonal hematopoiesis (CH) and inflammatory disease outcomes. The project aims to: 1) Determine the association between CH and rheumatologic diseases, 2) Identify CH genotypes...
The National Heart, Lung, and Blood Institute (NHLBI) has awarded a $751,747 Project Grant under the Cardiovascular Diseases Research (CFDA 93.837) program to the University of North Carolina at Chapel Hill. The grant, effective January 1, 2025 through November 30, 2028, will fund research to investigate the role of the CARM1 enzyme in regulating the transcriptional and post-transcriptional processes that control the maturation of cardiomyocytes, the most prevalent cells in the adult heart. This...
This $190,491 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), supports research to characterize the molecular markers in blood that are associated with the blood pressure response during acute exercise and their relationship to future hypertension and cardiovascular disease risk. The key activities under this 5-year award include: 1) identifying circulating proteins associated with the...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $802,301 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Weill Medical College of Cornell University. The grant, running from June 10, 2025 to April 30, 2029, aims to investigate the mechanisms by which mutated blood stem cells reorganize the local bone marrow niche environment to promote their own expansion, a key driver of clonal hematopoiesis, a condition that increases risk for...
The U.S. National Heart, Lung, and Blood Institute (NHLBI) awarded a $498,991.40 Project Grant to the University of Arkansas under the Cardiovascular Diseases Research (CFDA 93.837) federal grant program. The funding supports the development of microphysiological systems to study hypoxic cardiac injury resulting from acute myocardial infarction and ischemia-reperfusion injury. The research aims to engineer microfluidic devices to precisely control oxygen levels and investigate how oxygen...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $143,829 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to The University of Kentucky Research Foundation. The grant, effective January 1, 2025, supports a 5-year research project to: 1) establish human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) as models for studying how the intrinsic cardiomyocyte circadian clock impacts cell size and function, and 2) determine if genetic...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $422,894 to Miami University to investigate the interactive roles of cardiorespiratory fitness and adiposity on the recovery of impaired glucose control and vascular function following a period of reduced physical activity. The research aims to: 1) examine how existing health status...
This $132,410 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will provide protected time for Dr. Cheryl Anderson, a mid-career clinical investigator, to recruit and mentor a diverse group of trainees in clinical cardiovascular epidemiology and health equity research. The award will support two new areas of research: 1) integrating global policy and strategy into multilevel interventions to improve...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $735,085.00 to Case Western Reserve University (CWRU) to investigate the role of the Heat Shock Transcription Factor 1 (HSF1) in managing detrimental age-related clonal hematopoiesis (CH) and transforming it into a state that supports normal blood cell production. The research aims to understand how deleting HSF1 along with the...